2021 OTS Annual Meeting Poster Winner Showcase
Date: October 29th, 2021 Time: 7am-9am Pacific/ 10am-12pm Eastern/ 4pm-6pm Central European Time Description: Are you having post-event letdown now that the annual OTS meeting is over? We are too! Join us for this special 2-hour webinar to see presentations by four poster award ...
Non-Profits Create Next-Generation Medicines that Treat Ultra-Rare Diseases
Hundreds of millions of people worldwide are living with a rare disease. Most rare diseases do not currently have a cure. So, once diagnosed with a rare disease, most patients and their families are merely given strategies to manage the disease symptoms and try ...
Interview with Erin M. McConnell, PhD (Chemistry)
My introduction to the field was through functional nucleic acids called aptamers – small pieces of DNA that act as molecular recognition tools. I learned about them as an undergraduate student while completing my B.Sc. in neuroscience and chemistry at Carleton University, from Prof. Maria C. DeRosa, who would become my Ph.D. supervisor.
Oligonucleotides Safely Cross the Blood-Brain Barrier to Knock Down Gene Expression
Neurodegenerative diseases, brain tumors, and infectious diseases and inflammatory conditions that impact the brain wreak havoc on a person’s health and are notoriously difficult to treat. Oligonucleotide drugs could provide solutions to many pathological brain conditions if certain challenges could be overcome. Researchers at ...
Ligand Conjugation – Expanding the Reach of Oligonucleotide Therapeutics
Oligonucleotide therapies possess enormous potential as healing, life-changing, and cancer-curing drugs. However, there are many barriers to utilizing oligonucleotides to treat disease. Discovering or creating effective delivery methods for each target cell or tissue type solves many of these problems and there are multiple ...
OTS President’s Paper Pick – August 2021
By: Annemieke Aartsma-Rus, Ph.D. The paper information: CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis Julian D Gillmore, Ed Gane, Jorg Taube, Justin Kao, Marianna Fontana, Michael L Maitland, Jessica Seitzer, Daniel O’Connell, Kathryn R Walsh, Kristy Wood, Jonathan Phillips, Yuanxin Xu, Adam Amaral, Adam ...
Presentations & Networking in a Virtual World
Presenter: Aurélie Lacroix, PhD, Sixfold Bioscience Keith T. Gagnon, Ph.D, Southern Illinois University School of Medicine Date: 25 August 2021 Time: 8am Pacific / 11am Eastern / 5m Central Description: Join us for a presentation of tips & tricks for making the most of ...
Maximize Your Involvement in the OTS Community
Presenter: Erin M. McConnell, Ph.D.,University of Ottawa Annemieke Aartsma-Rus, PhD, OTS President,Leiden University Medical Center Date: June 24, 2021 Time: 8am Pacific/11am Eastern/5pm Central European Time  Description: Do you study how oligonucleotides can be used as therapeutics? Are you new to the OTS? ...
Lipid Nanoparticles: Nanomedicine’s Triumph
Oligonucleotide therapeutics have been making headlines this past year, between the groundbreaking new mRNA vaccines and the recent news of phenomenal interim results for Intellia’s investigational genome editing treatment for ATTR amyloidosis. Neither of these would have been possible without a lesser-known component – ...
Interview with Tom Brown, PhD
Tom Brown Ph.D. Professor of Nucleic Acid Chemistry University of Oxford, Founder of ATDBio Ltd (and now Chief consultant). Â How did you become interested in the field of oligonucleotides? All my family members were manual workers, and I was the first to go ...
