Recent Articles2022-03-14T07:39:44+00:00
9May, 2022

Could Artificial Intelligence Provide the Key to Life Saving Medicines?

Categories: Featured Perspectives On Current Science|

Drug discovery is time consuming and expensive, requiring trial and error screening. This means that many people have to wait decades, or a lifetime, to find a treatment for their disease. Others, especially those with rare diseases, may never have hope of a treatment. However, AI and deep learning [...]

22April, 2022

A Novel Cocktail Drug Penetrates Heart Muscle and May Treat Nearly Half of All Patients with DMD

Categories: Featured Perspectives On Current Science|

Duchenne muscular dystrophy (DMD) is a devastating disease that causes the body's muscle tissues to progressively waste away until all mobility is lost. Eventually, the heart muscle becomes fatty and fibrotic, typically leading to heart failure and death by age 30. There is no cure, and the approved drugs [...]

9March, 2022

Support for Ukrainian Scientists

Categories: Perspectives on Current Science|

The OTS joins other scientific organizations in seeking to help Ukrainian scientists. Specifically, we invite Ukrainian students, scientists, and industry professionals with interests in the field of nucleic acids and oligonucleotide therapeutics to post their contact information and CVs on the OTS website. We ask our membership to spread [...]

28February, 2022

A New ASO Shows Promise in Treating Dravet Syndrome, a Severe Form of Epilepsy

Categories: Featured Perspectives On Current Science, Perspectives on Current Science|

Typically, a single copy of a gene is enough to support normal growth and development but in a small subset of genes, the loss of one copy can cause serious diseases that are often difficult to treat. One of these conditions, Dravet Syndrome, has no treatment options that directly [...]

9February, 2022

A Potent ASO Shows Encouraging Results in A Single-Patient Pilot Study for ALS

Categories: Perspectives on Current Science|

Amyotrophic lateral sclerosis (ALS) is a progressive, neurodegenerative disease in which motor neurons die. Since the motor neurons that die control voluntary muscles, the disease causes great difficulty for those who must live with it. They will experience loss of motor control of the arms and legs which causes [...]

19January, 2022

Does CRISPR Gene Editing Increase the Risk of Developing Cancer?

Categories: Perspectives on Current Science|

CRISPR is a useful tool in a wide array of applications, and one of the most headline-grabbing is its potential in gene editing. As with any new technology or medication, there are inherent risks that must be discovered and mitigated. This is especially true in the arena of gene-editing, [...]

1January, 2022

Clinical Trials Begin for Ultra-Rare Treatment of Alexander Disease

Categories: Featured Perspectives On Current Science, Perspectives on Current Science|

It is always exciting to observe phenomenal results in the treatment of a disease in animal studies, and even more so to see them move into clinical trials. ASOs have proven to be efficient at providing deep reductions in disease causing proteins, and a treatment that produced significant results [...]

24December, 2021

Looking back… Looking forward

Categories: Blog|

This will be my last contribution that I write as President of our Society. On January 1st, 2022, I will become ‘Immediate Past-President’. David Corey (University of Texas, Southwestern) will take over as President and Richard Geary (Ionis Pharmaceuticals) will become the Society’s next President-Elect. As we delayed this [...]

A Novel Cocktail Drug Penetrates Heart Muscle and May Treat Nearly Half of All Patients with DMD

April 22nd, 2022|Categories: Featured Perspectives On Current Science|

Duchenne muscular dystrophy (DMD) is a devastating disease that causes the body's muscle tissues to progressively waste away until all mobility is lost. Eventually, the heart muscle becomes fatty [...]

A New ASO Shows Promise in Treating Dravet Syndrome, a Severe Form of Epilepsy

February 28th, 2022|Categories: Featured Perspectives On Current Science, Perspectives on Current Science|

Typically, a single copy of a gene is enough to support normal growth and development but in a small subset of genes, the loss of one copy can cause [...]

Comments Off on A New ASO Shows Promise in Treating Dravet Syndrome, a Severe Form of Epilepsy

A Potent ASO Shows Encouraging Results in A Single-Patient Pilot Study for ALS

February 9th, 2022|Categories: Perspectives on Current Science|

Amyotrophic lateral sclerosis (ALS) is a progressive, neurodegenerative disease in which motor neurons die. Since the motor neurons that die control voluntary muscles, the disease causes great difficulty for [...]

Comments Off on A Potent ASO Shows Encouraging Results in A Single-Patient Pilot Study for ALS

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