Oligonucleotide Therapeutics Society

Antisense Oligonucleotide-based Therapies for Inherited Retinal Diseases: From Mutation to Clinical Trial

March 1st, 2022|Categories: Past Webinars|

Speaker: Alex Garanto, PhD Date: March 10, 2022 Time: 11-12 EST Description: The eye is at the forefront of therapeutic development for its unique properties. Local delivery of ASOs to the retina has shown to be well tolerated and safe. During this webinar, Prof. [...]

A Perspective From Industry – A Conversation With Richard S. Geary, Ph.D. Executive Vice President, Chief Development Officer at Ionis Pharmaceuticals

February 3rd, 2022|Categories: Past Webinars|

Speaker: Richard S. Geary, Ph.D. Date: February 10, 2022 Time: 11-12 EST Description: The OTS Webinar series is pleased to feature Dr. Richard Geary, the current President Elect, and the Executive Vice President, Chief Development Officer at Ionis Pharmaceuticals. For part of the webinar [...]

How to test for immune activation by your therapeutic oligonucleotide

June 18th, 2021|Categories: Past Webinars|

Presenter: Arthur M. Krieg, MD, Checkmate Pharmaceuticals Date: 19 April 2018 Description: RNA and DNA oligonucleotides with charged backbones commonly cause immune activation, which can be recognized by appropriate in vitro and/or in vivo testing. Eukaryotic innate immune systems have evolved multiple receptors to [...]

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