Realizing the Promise of CRISPR Therapeutics: In Vivo and Cell Therapy Applications
Time: 8am Pacific | 11am Eastern | 5pm CET Date: May 11, 2023 Laura will be discussing preclinical and clinical data for CRISPR based investigational drug candidates from Intellia Therapeutics. Speakers: Laura Sepp-Lorenzino, ...
The World of GalNAc-Conjugates in Nucleic Acid Therapeutics
Time: 5pm Amsterdam - 9 AM MST Date: April 27, 2023 Speakers: Mano Manoharan, PhD View Bio
Trainee Spotlight Series: Jeremy Hall and Tracy Mallette
Time: 5pm Amsterdam Date: April 13, 2023 Topics/Speakers: Oligo-PROTAC strategy for cell-selective and targeted degradation of activated STAT3 Jeremy Hall City of Hope & Keck Graduate Institute Jeremy will present a summary of the ...
Trainee Spotlight Series: OTS 2022 poster winners
Time: 05:00 PM - Amsterdam, Berlin, Rome, Stockholm, Vienna Date: March 30, 2023 Topics/Speakers: Therapeutic application of engineered U1 snRNAs in retinopathies and other disorders Paolo Pigini Assessing efficacy ...
Spotting Stubborn Indirect Effects in Oligonucleotide Therapeutics
Time: 4pm CET Date: March 16, 2023 We use chemistry to improve the properties of nucleic acid therapeutics including antisense oligonucleotides, siRNAs, and genome editing approaches. I will walk through a recent study we carried out trying to activate frataxin expression to treat ...
Towards Developing Greener Methods for Oligonucleotide Synthesis
Time: 5pm Amsterdam - 9 AM MST Date: February 23, 2023 Research: My research focuses on the development of novel methodologies for oligonucleotide synthesis, with a particular emphasis on reducing the solvent footprint of oligonucleotide synthesis. Webinar topic: My webinar will largely focus on ...
Trainee Spotlight Series: OTS 2023 Junior Board Members
Time: 5pm Amsterdam - 9 AM MST Date: February 9, 2023 Speakers: Krystal Johnson, MSc Investigating the consequences of nuclear AGO2 in colon cancer model systems View Bio Description Argonaute proteins ...
Trainee Spotlight Series: OTS 2022 Poster Winners
Time: 5pm Amsterdam - 9 AM MST Date: January 26th, 2023 Topic / Speakers: Quantitative measurement of cytosolic and nuclear penetration of oligonucleotide therapeutics and investigation of sequence-penetration relationships Nefeli Batistatou, MSc Nefeli Batistatou, ...
Delivery of Chemically Stabilized RNAi molecules to the Central Nervous System
Time: 11am - 12pm ESTDate: December 1, 2022 Description: Dr. Godinho will talk about the developments on delivery and PK/PD of novel oligonucleotides for CNS applications Speaker: Bruno M.D.C. Godinho Sr. Scientist Atalanta Therapeutics ...
An insider’s view into the preclinical development of an approved exon skipping drug
Time: 11am - 12pm EST Date: November 3, 2022 Description: Dr. Arechavala works on developing new drugs for neuromuscular disorders. As there are not many for these rare diseases, neuromuscular disorders have been at the forefront of the clinical development of RNA based ...