The Oligonucleotide Therapeutics Society (OTS) is an open, nonprofit forum to foster research and development of oligonucleotide therapeutics.
The Founders’ vision was to bring together the expertise from different angles of oligonucleotide research to create synergies and to bring the field of oligonucleotides to its full therapeutic potential. A new era of oligonucleotide drugs was envisioned that would change the landscape of therapeutic modalities.
Oligonucleotide therapeutics are now being used to successfully treat diseases and have the potential for widespread application. Over 100 treatments are in development for common conditions, including cancer and Alzheimer’s disease, as well as rare diseases. Incredibly, oligonucleotide therapeutics have also been used to create an individualized treatment for one single person with a rare, fatal disease.
All the latest news
FEATURED ARTICLE
Eplontersen May Soon Provide Another Safe, Effective Treatment for People Diagnosed with ATTR
FEATURED ARTICLE
The Personal Journey of Stanley Crooke, the Creation and Development of Ionis, and Beyond
A Landmark Permanent Treatment for Children Born with a Deadly Immune Disorder
In June 2022, the first stem cell gene therapy of Dutch origin was successfully given to a patient by ...
Treating Cardiovascular Disease by Changing a Single Letter of DNA
A simple spelling change in liver DNA could improve the future of cardiovascular disease treatment. On July 12, biotechnology ...
FDA Draft Guidance – An Exciting Step in the Journey to Bring Oligonucleotide Therapeutics to Patients
In recent years, antisense and small interfering RNA (siRNA) oligonucleotide therapeutics have been FDA-approved to treat rare diseases, and many ...
Featured Member
Pawan Kumar, PhD
Principal Scientist, Takeda Pharmaceuticals
I was fascinated by tremendous therapeutic potential antisense oligonucleotides offered for rare conditions that were previously thought untreatable. My goal is to make a significant contribution towards delivering therapeutic oligonucleotides to extra hepatic tissues.
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