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Another stellar review article summarizing the field now published in Nucleic Acid Therapeutics. The review in Nucleic Acid Therapeutics by Jillian Belgrad and colleagues discusses the significant progress and future potential of nucleic acid-based therapies (NATs). It highlights the historical milestones, including the approval of over 20 NAT products and hundreds of ongoing clinical trials. The review addresses the major challenges faced by NATs, such as delivery into biological systems, stability, and targeted distribution, while also showcasing the key innovations that are expanding the capabilities of NATs. These advancements are setting the stage for NATs to become a new drug class, offering hope for patients with previously incurable diseases.
