Engineered anti-CRISPR proteins for optogenetic control of CRISPR-Cas9
Bubeck F, Hoffmann MD, Harteveld Z, Aschenbrenner S, Bietz A, Waldhauer MC, Börner K, Fakhiri J, Schmelas C, Dietz L, Grimm D, Correia BE, Eils R, Niopek D. Nat Methods. 2018 Nov;15(11):924-927. PubMed
Genome-wide screening for functional long noncoding RNAs in human cells by Cas9 targeting of splice sites
Liu Y, Cao Z, Wang Y, Guo Y, Xu P, Yuan P, Liu Z, He Y, Wei W. Nat Biotechnol. 2018 Nov 5. PubMed
Correction of the Marfan Syndrome Pathogenic FBN1 Mutation by Base Editing in Human Cells and Heterozygous Embryos
Zeng Y, Li J, Li G, Huang S, Yu W, Zhang Y, Chen D, Chen J, Liu J, Huang X. Mol Ther. 2018 Nov 7;26(11):2631-2637. PubMed
Predictable and precise template-free CRISPR editing of pathogenic variants
Shen MW, Arbab M, Hsu JY, Worstell D, Culbertson SJ, Krabbe O, Cassa CA, Liu DR, Gifford DK, Sherwood RI. Nature. 2018 Nov;563(7733):646-651. PubMed
Nanoparticles That Deliver RNA to Bone Marrow Identified by in Vivo Directed Evolution
Sago CD, Lokugamage MP, Islam FZ, Krupczak BR, Sato M, Dahlman JE. J Am Chem Soc. 2018 Nov 16. PubMed
CRISPR-Sirius: RNA scaffolds for signal amplification in genome imaging
Ma H, Tu LC, Naseri A, Chung YC, Grunwald D, Zhang S, Pederson T. Nat Methods. 2018 Nov;15(11):928-931. PubMed
Current Strategies for Site-Directed RNA editing using ADARs
Montiel-Gonzalez MF, Quiroz JFD, Rosenthal JJC. Methods. 2018 Nov 28. pii: S1046-2023(18)30197-X. PubMed
Optimized base editors enable efficient editing in cells, organoids and mice
Zafra MP, Schatoff EM, Katti A, Foronda M, Breinig M, Schweitzer AY, Simon A, Han T, Goswami S, Montgomery E, Thibado J, Kastenhuber ER, Sánchez-Rivera FJ, Shi J, Vakoc CR, Lowe SW, Tschaharganeh DF, Dow LE. Nat Biotechnol. 2018 Oct;36(9):888-893. PubMed
Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction
Koblan LW, Doman JL, Wilson C, Levy JM, Tay T, Newby GA, Maianti JP, Raguram A, Liu DR. Nat Biotechnol. 2018 Oct;36(9):843-846. PubMed
Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy
Amoasii L, Hildyard JCW, Li H, Sanchez-Ortiz E, Mireault A, Caballero D, Harron R, Stathopoulou TR, Massey C, Shelton JM, Bassel-Duby R, Piercy RJ, Olson EN. Science. 2018 Oct 5;362(6410):86-91. PubMed