How to Develop and Prove High-Efficiency Selection of Ligands from Oligonucleotide Libraries: A Universal Framework for Aptamers and DNA-Encoded Small-Molecule Ligands
Papers of interest to society members in the field of oligonucleotide therapeutics. Antisense, aptamers, lncRNA, siRNA, splice modulation and ribozymes.
Recent progress in non-native nucleic acid modifications
Papers of interest to society members in the field of oligonucleotide therapeutics. Antisense, aptamers, lncRNA, siRNA, splice modulation and ribozymes.
Antisense Technology: A Review.
Papers of interest to society members in the field of oligonucleotide therapeutics. Antisense, aptamers, lncRNA, siRNA, splice modulation and ribozymes.
Best practices to ensure robust investigation of circular RNAs: pitfalls and tips
Papers of interest to society members in the field of oligonucleotide therapeutics. Antisense, aptamers, lncRNA, siRNA, splice modulation and ribozymes.
A Hitchhiker’s Guide to Click-Chemistry with Nucleic Acids
Fantoni NZ, El-Sagheer AH, Brown T. Chem Rev. 2021 Jan 14. Pubmed
Clinical Pharmacology Studies Supporting Oligonucleotide Therapy Development: An Assessment of Therapies Approved and in Development Between 2012-2018
Rogers H, Adeniyi O, Ramamoorthy A, Bailey S, Pacanowski M. Clin Transl Sci. 2020 Dec 5. Pubmed
Design and application of circular RNAs with protein-sponge function
Schreiner S, Didio A, Hung LH, Bindereif A. Nucleic Acids Res. 2020 Nov 24:gkaa1085 Pubmed
Modified aptamers as reagents to characterize recombinant human erythropoietin products
Jankowski W, Lagassé HAD, Chang WC, McGill J, Jankowska KI, Gelinas AD, Janjic N, Sauna ZE. Sci Rep. 2020 Oct 29;10(1):18593. Pubmed
Crosstalk between RNA m6A Modification and Non-coding RNA Contributes to Cancer Growth and Progression
Dai F, Wu Y, Lu Y, An C, Zheng X, Dai L, Guo Y, Zhang L, Li H, Xu W, Gao W. Mol Ther Nucleic Acids. 2020 Aug 8;22:62-71. Pubmed
Antisense Drug Discovery and Development Technology Considered in a Pharmacological Context
Crooke ST, Liang XH, Crooke RM, Baker BF, Geary RS. Biochem Pharmacol. 2020 Aug 12:114196. Pubmed