CRISPR-SKIP: programmable gene splicing with single base editors
Gapinske M, Luu A, Winter J, Woods WS, Kostan KA, Shiva N, Song JS, Perez-Pinera P. Genome Biol. 2018 Aug 15;19(1):107. PubMed
Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing
Mir A, Alterman JF, Hassler MR, Debacker AJ, Hudgens E, Echeverria D, Brodsky MH, Khvorova A, Watts JK, Sontheimer EJ. Nat Commun. 2018 Jul 6;9(1):2641. PubMed
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs
Vogel P, Moschref M, Li Q, Merkle T, Selvasaravanan KD, Li JB, Stafforst T. Nat Methods. 2018 Jul;15(7):535-538. PubMed
Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID
Sasaguri H, Nagata K, Sekiguchi M, Fujioka R, Matsuba Y, Hashimoto S, Sato K, Kurup D, Yokota T, Saido TC. Nat Commun. 2018 Jul 24;9(1):2892. PubMed
In vivo base editing of post-mitotic sensory cells
Yeh WH, Chiang H, Rees HA, Edge ASB, Liu DR. Nat Commun. 2018 Jun 5;9(1):2184. PubMed
Efficient RNA drug delivery using red blood cell extracellular vesicles
Usman WM, Pham TC, Kwok YY, Vu LT, Ma V, Peng B, Chan YS, Wei L, Chin SM, Azad A, He AB, Leung AYH, Yang M, Shyh-Chang N, Cho WC, Shi J, Le MTN. Nat Commun. 2018 Jun 15;9(1):2359. PubMed
Chemically Modified Cpf1-CRISPR RNAs Mediate Efficient Genome Editing in Mammalian Cells
McMahon MA, Prakash TP, Cleveland DW, Bennett CF, Rahdar M. Mol Ther. 2018 May 2;26(5):1228-1240. PubMed
Dose-Dependent Prevention of Metabolic and Neurologic Disease in Murine MPS II by ZFN-Mediated In Vivo Genome Editing
Laoharawee K, DeKelver RC, Podetz-Pedersen KM, Rohde M, Sproul S, Nguyen HO, Nguyen T, St Martin SJ, Ou L, Tom S, Radeke R, Meyer KE, Holmes MC, Whitley CB, Wechsler T, McIvor RS. Mol Ther. 2018 Apr 4;26(4):1127-1136. PubMed
Incorporation of bridged nucleic acids into CRISPR RNAs improves Cas9 endonuclease specificity
Cromwell CR, Sung K, Park J, Krysler AR, Jovel J, Kim SK, Hubbard BP. Nat Commun. 2018 Apr 13;9(1):1448. PubMed
RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors
Thakore PI, Kwon JB, Nelson CE, Rouse DC, Gemberling MP, Oliver ML, Gersbach CA. Nat Commun. 2018 Apr 26;9(1):1674. PubMed