Centyrin ligands for extrahepatic delivery of siRNA.
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Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell
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siRNAs containing 2′-fluorinated Northern-methanocarbacyclic (2′-F-NMC) nucleotides: in vitro and in vivo RNAi activity and inability of mitochondrial polymerases to incorporate 2′-F-NMC NTPs
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Perspectives on the Designation of Oligonucleotide Starting Materials
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Site-specific incorporation of 5′-methyl DNA enhances the therapeutic profile of gapmer ASOs.
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Bispecific Aptamer Chimeras Enable Targeted Protein Degradation on Cell Membranes
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Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents
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Systemic delivery of antagomirs during blood brain barrier disruption is disease-modifying in experimental epilepsy
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The HIF-1α antisense long non-coding RNA drives a positive feedback loop of HIF-1α mediated transactivation and glycolysis
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Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH
SimĂ³n J, Goikoetxea-Usandizaga N, Serrano-MaciĂ¡ M, FernĂ¡ndez-Ramos D, SĂ¡enz de Urturi D, Gruskos JJ, FernĂ¡ndez-Tussy P, Lachiondo-Ortega S, GonzĂ¡lez-Recio I, RodrĂguez-Agudo R, GutiĂ©rrez-de-Juan V, RodrĂguez-Iruretagoyena B, Varela-Rey M, Gimenez-Mascarell P, Mercado-Gomez M, GĂ³mez-Santos B, Fernandez-Rodriguez C, Lopitz-Otsoa F, Bizkarguenaga M, Dames S, Schaeper U, Martin ...
