SELEX methods on the road to protein targeting with nucleic acid aptamers
Bayat P, Nosrati R, Alibolandi M, Rafatpanah H, Abnous K, Khedri M, Ramezani M. Biochimie. 2018 Sep 5;154:132-155. PubMed
Aptamers as Diagnostic Tools in Cancer
Ruiz Ciancio D, Vargas MR, Thiel WH, Bruno MA, Giangrande PH, Mestre MB. Pharmaceuticals (Basel). 2018 Sep 11;11(3). PubMed
Precision Medicine through Antisense Oligonucleotide-Mediated Exon Skipping
Li D, Mastaglia FL, Fletcher S, Wilton SD. Trends Pharmacol Sci. 2018 Sep 30. pii: S0165-6147(18)30145-7. PubMed
The Three S’s for Aptamer-Mediated Control of DNA Nanostructure Dynamics: Shape, Self-Complementarity, and Spatial Flexibility
Shiu SC, Kinghorn AB, Sakai Y, Cheung YW, Heddle JG, Tanner JA. Chembiochem. 2018 Sep 17;19(18):1900-1906. PubMed
Antisense oligonucleotides correct the familial dysautonomia splicing defect in IKBKAP transgenic mice
Sinha R, Kim YJ, Nomakuchi T, Sahashi K, Hua Y, Rigo F, Bennett CF, Krainer AR. Nucleic Acids Res. 2018 Jun 1;46(10):4833-4844. The three joint first authors: Rahul Sinha Young Jin Kim Tomoki Nomakuchi Currently, the most successful oligonucleotide ...
2018 Paper of the Year Award Winner: Alejandra Gonzalez-Duarte, MD
Dr. Alejandra Gonzalez-Duarte, MDNational Institute of Medical Sciences and Nutrition–Salvador Zubiran, MexicoTalk Title: Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin AmyloidosisA.Gonzalez‑Duarte1, D. Adams2, W.D. O’Riordan3, C.-C. Yang4, M. Ueda5, A.V. Kristen6, I. Tournev7, H.H. Schmidt8, T. Coelho9, J.L. Berk10, K.-P. Lin11, G. Vita12, S. Attarian13, ...
2018 OTS Travel Grant Recipients
Philippinne Aupy, INSERM U1179 Versailles Saint Quentin University Iris Barny, MS, Institute of Genetics Diseases, Imagine Cansu Colpan, MSc., University of Massachusetts Medical School Ahmed ElDesoky, University of Sadat City Chantal Ferguson, BA, University of Massachusetts Medical School Oksana Goroshchuk, MD, PhD Student, Karolinska Institutet ...
2018 OTS Young Investigator Award Winner Yizhou Dong, PhD
Yizhou Dong, PhD Associate Professor The Ohio State University College of Pharmacy Division of Pharmaceutics and Pharmaceutical Chemistry 434 Riffe Building, 500 West 12th Avenue, Columbus, OH 43210 Office: 614-292-3771 Email: dong.525@osu.edu Biography: Yizhou Dong is an Associate Professor ofCollege of Pharmacy at The Ohio ...
Interview with Zheng-Rong Lu, PhD
I was attracted to the field of nucleic acid therapeutics by the news of 2006 Nobel Prize in Medicine to Andrew Fire and Craig Mello when I was a junior