Blocking Stemness and Metastatic Properties of Ovarian Cancer Cells by Targeting p70S6K with Dendrimer Nanovector-Based siRNA Delivery
Ma J, Kala S, Yung S, Chan TM, Cao Y, Jiang Y, Liu X, Giorgio S, Peng L, Wong AST. Mol Ther. 2018 Jan 3;26(1):70-83. PubMed
Upregulation of the long non-coding RNA AFAP1-AS1 affects the proliferation, invasion and survival of tongue squamous cell carcinoma via the Wnt/β-catenin signaling pathway
Wang ZY, Hu M, Dai MH, Xiong J, Zhang S, Wu HJ, Zhang SS, Gong ZJ. Mol Cancer. 2018 Jan 8;17(1):3. PubMed
TGF-β Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis
Feng M, Tang PM, Huang XR, Sun SF, You YK, Xiao J, Lv LL, Xu AP, Lan HY. Mol Ther. 2018 Jan 3;26(1):148-161. PubMed
Silencing of the lncRNA Zeb2-NAT facilitates reprogramming of aged fibroblasts and safeguards stem cell pluripotency
Bernardes de Jesus B, Marinho SP, Barros S, Sousa-Franco A, Alves-Vale C, Carvalho T, Carmo-Fonseca M. Nat Commun. 2018 Jan 8;9(1):94. PubMed
Local and sustained miRNA delivery from an injectable hydrogel promotes cardiomyocyte proliferation and functional regeneration after ischemic injury
Wang LL, Liu Y, Chung JJ, Wang T, Gaffey AC, Lu M, Cavanaugh CA, Zhou S, Kanade R, Atluri P, Morrisey EE, Burdick JA. Nat Biomed Eng. 2017;1:983-992. PubMed
A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes
Serr I, Scherm MG, Zahm AM, Schug J, Flynn VK, Hippich M, Kälin S, Becker M, Achenbach P, Nikolaev A, Gerlach K, Liebsch N, Loretz B, Lehr CM, Kirchner B, Spornraft M, Haase B, Segars J, KĂ¼per C, Palmisano R, Waisman A, Willis RA, Kim ...
The miR-21/PDCD4/AP-1 feedback loop function as a driving force for renal fibrogenesis
Sun Q, Miao J, Luo J, Yuan Q, Cao H, Su W, Zhou Y, Jiang L, Fang L, Dai C, Zen K, Yang J. J Cell Sci. 2018 Jan 19. pii: jcs.202317. PubMed
MicroRNA-149-5p regulates blood-brain barrier permeability after transient middle cerebral artery occlusion in rats by targeting S1PR2 of pericytes
Wan Y, Jin HJ, Zhu YY, Fang Z, Mao L, He Q, Xia YP, Li M, Li Y, Chen X, Hu B. FASEB J. 2018 Jan 18:fj201701121R. PubMed
Design and implementation of a synthetic pre-miR switch for controlling miRNA biogenesis in mammals
Atanasov J, Groher F, Weigand JE, Suess B. Nucleic Acids Res. 2017 Dec 15;45(22):e181. PubMed
Personalized RNA-medicine for pancreatic cancer
Gilles ME, Hao L, Huang L, Rupaimoole R, Lopez-Casas PP, Pulver E, Jeong JC, Muthuswamy SK, Hidalgo M, Bhatia SN, Slack FJ. Clin Cancer Res. 2018 Jan 12. pii: clincanres.2733.2017. PubMed