Base editing with a Cpf1-cytidine deaminase fusion
Li X, Wang Y, Liu Y, Yang B, Wang X, Wei J, Lu Z, Zhang Y, Wu J, Huang X, Yang L, Chen J. Nat Biotechnol. 2018 Apr;36(4):324-327. PubMed
Simultaneous Monitoring of Cell-surface Receptor and Tumor-targeted Photodynamic Therapy via TdT-initiated Poly-G-Quadruplexes
Shi T, Wang M, Li H, Wang M, Luo X, Huang Y, Wang HH, Nie Z, Yao S. Sci Rep. 2018 Apr 3;8(1):5551. PubMed
Tunable cytotoxic aptamer-drug conjugates for the treatment of prostate cancer
Powell Gray B, Kelly L, Ahrens DP, Barry AP, Kratschmer C, Levy M, Sullenger BA. Proc Natl Acad Sci U S A. 2018 Apr 16. pii: 201717705. PubMed
Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery
Wolfe JM, Fadzen CM, Choo ZN, Holden RL, Yao M, Hanson GJ, Pentelute BL. ACS Cent Sci. 2018 Apr 25;4(4):512-520. PubMed
Polymer-Mediated Inhibition of Pro-invasive Nucleic Acid DAMPs and Microvesicles Limits Pancreatic Cancer Metastasis
Naqvi I, Gunaratne R, McDade JE, Moreno A, Rempel RE, Rouse DC, Herrera SG, Pisetsky DS, Lee J, White RR, Sullenger BA. Mol Ther. 2018 Apr 4;26(4):1020-1031. PubMed
Chronic Toxicity Assessment of 2′-O-Methoxyethyl Antisense Oligonucleotides in Mice
Zanardi TA, Kim TW, Shen L, Serota D, Papagiannis C, Park SY, Kim Y, Henry SP. Nucleic Acid Ther. 2018 Apr 30. PubMed
Intracerebroventricular Administration of a 2′-O-Methyl Phosphorothioate Antisense Oligonucleotide Results in Activation of the Innate Immune System in Mouse Brain
Toonen LJA, Casaca-Carreira J, Pellisé-Tintoré M, Mei H, Temel Y, Jahanshahi A, van Roon-Mom WMC. Nucleic Acid Ther. 2018 Apr;28(2):63-73. PubMed
Systemic administration of the antisense oligonucleotide NS-065/NCNP-01 for skipping of exon 53 in patients with Duchenne muscular dystrophy
Komaki H, Nagata T, Saito T, Masuda S, Takeshita E, Sasaki M, Tachimori H, Nakamura H, Aoki Y, Takeda S. Sci Transl Med. 2018 Apr 18;10(437). PubMed
Systematic Analysis of Splice-Site-Creating Mutations in Cancer
Jayasinghe RG, Cao S, Gao Q, Wendl MC, Vo NS, Reynolds SM, Zhao Y, Climente-González H, Chai S, Wang F, Varghese R, Huang M, Liang WW, Wyczalkowski MA, Sengupta S, Li Z, Payne SH, Fenyö D, Miner JH, Walter MJ; Cancer Genome Atlas Research Network, ...
Evolution of sequence-defined highly functionalized nucleic acid polymers
Chen Z, Lichtor PA, Berliner AP, Chen JC, Liu DR. Nat Chem. 2018 Apr;10(4):420-427. PubMed
