Hybridization Liquid Chromatography-Tandem Mass Spectrometry: An Alternative Bioanalytical Method for Antisense Oligonucleotide Quantitation in Plasma and Tissue Samples.
Li P, Gong Y, Kim J, Liu X, Gilbert J, Kerns HM, Groth R, Rooney M. Anal Chem. 2020 Jul 17. Pubmed
Rational design of antisense oligonucleotides modulating the activity of TLR7/8 agonists
Alharbi AS, Garcin AJ, Lennox KA, Pradeloux S, Wong C, Straub S, Valentin R, Pépin G, Li HM, Nold MF, Nold-Petry CA, Behlke MA, Gantier MP. Nucleic Acids Res. 2020 Jun 16:gkaa523. Pubmed
Nanoparticle delivery of immunostimulatory oligonucleotides enhances response to checkpoint inhibitor therapeutics.
Buss CG, Bhatia SN. Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13428-13436. Pubmed
Safety, Tolerability, and Efficacy of Viltolarsen in Boys with Duchenne Muscular Dystrophy Amenable to Exon 53 Skipping: A Phase 2 Randomized Clinical Trial
Clemens PR, Rao VK, Connolly AM, Harper AD, Mah JK, Smith EC, McDonald CM, Zaidman CM, Morgenroth LP, Osaki H, Satou Y, Yamashita T, Hoffman EP; CINRG DNHS Investigators. JAMA Neurol. 2020 May 26 Pubmed
Vaccination against non-mutated neoantigens induced in recurrent and future tumors
Garrido G, Schrand B, Levay A, Rabasa Capote A, Ferrantella A, Da Silva DM, D'Eramo F, Marijt KA, Zhang Z, Kwon D, Kortylewski M, Kast WM, Dudeja V, van Hall T, Gilboa E. Cancer Immunol Res. 2020 Apr 15. PubMed
Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses
Leong WI, Ames RY, Haverkamp JM, Torres L, Kline J, Bans A, Rocha L, Gallotta M, Guiducci C, Coffman RL, Janatpour MJ. Oncotarget. 2019 Dec 31;10(68):7220-7237. PubMed
Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization.
Lemke-Miltner CD, Blackwell SE, Yin C, Krug AE, Morris AJ, Krieg AM, Weiner GJ. J Immunol. 2020 Jan 17. pii: ji1900742. PubMed
Sequence Multiplicity within Spherical Nucleic Acids.
Huang ZN, Cole LE, Callmann CE, Wang S, Mirkin CA. ACS Nano. 2020 Jan 28;14(1):1084-1092. PubMed
Targeting Extracellular miR-21-TLR7 Signaling Provides Long-Lasting Analgesia in Osteoarthritis.
Hoshikawa N, Sakai A, Takai S, Suzuki H. Mol Ther Nucleic Acids. 2019 Nov 20;19:199-207. PubMed
Immunogenicity and safety of a 2-dose hepatitis B vaccine, HBsAg/CpG 1018, in persons with diabetes mellitus aged 60-70 years
Hyer RN, Janssen RS. Vaccine. 2019 Sep 16;37(39):5854-5861. PubMed