2018 Paper of the Year Award Winner: Alejandra Gonzalez-Duarte, MD
Dr. Alejandra Gonzalez-Duarte, MDNational Institute of Medical Sciences and Nutrition–Salvador Zubiran, MexicoTalk Title: Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin AmyloidosisA.Gonzalez‑Duarte1, D. Adams2, W.D. O’Riordan3, C.-C. Yang4, M. Ueda5, A.V. Kristen6, I. Tournev7, H.H. Schmidt8, T. Coelho9, J.L. Berk10, K.-P. Lin11, G. Vita12, S. Attarian13, ...
2018 OTS Travel Grant Recipients
Philippinne Aupy, INSERM U1179 Versailles Saint Quentin University Iris Barny, MS, Institute of Genetics Diseases, Imagine Cansu Colpan, MSc., University of Massachusetts Medical School Ahmed ElDesoky, University of Sadat City Chantal Ferguson, BA, University of Massachusetts Medical School Oksana Goroshchuk, MD, PhD Student, Karolinska Institutet ...
2018 OTS Young Investigator Award Winner Yizhou Dong, PhD
Yizhou Dong, PhD Associate Professor The Ohio State University College of Pharmacy Division of Pharmaceutics and Pharmaceutical Chemistry 434 Riffe Building, 500 West 12th Avenue, Columbus, OH 43210 Office: 614-292-3771 Email: dong.525@osu.edu Biography: Yizhou Dong is an Associate Professor ofCollege of Pharmacy at The Ohio ...
Interview with Zheng-Rong Lu, PhD
I was attracted to the field of nucleic acid therapeutics by the news of 2006 Nobel Prize in Medicine to Andrew Fire and Craig Mello when I was a junior
Antisense oligonucleotide targeting of mRNAs encoding ENaC subunits α, β, and γ improves cystic fibrosis-like disease in mice
Zhao C, Crosby J, Lv T, Bai D, Monia BP, Guo S. J Cyst Fibros. 2018 Aug 10. PubMed
Epigenetic reprogramming with antisense oligonucleotides enhances the effectiveness of androgen receptor inhibition in castration-resistant prostate cancer
Xiao L, Tien JC, Vo J, Tan M, Parolia A, Zhang Y, Wang L, Qiao Y, Shukla S, Wang X, Zheng H, Su F, Jing X, Luo E, Delekta A, Juckette KM, Xu A, Cao X, Alva AS, Kim Y, Macleod AR, Chinnaiyan AM. Cancer ...
Functional features defining the efficacy of cholesterol-conjugated, self-deliverable, chemically modified siRNAs
Shmushkovich T, Monopoli KR, Homsy D, Leyfer D, Betancur-Boissel M, Khvorova A, Wolfson AD. Nucleic Acids Res. 2018 Aug 29. PubMed
Specific Inhibition of Hepatic Lactate Dehydrogenase Reduces Oxalate Production in Mouse Models of Primary Hyperoxaluria
Lai C, Pursell N, Gierut J, Saxena U, Zhou W, Dills M, Diwanji R, Dutta C, Koser M, Nazef N, Storr R, Kim B, Martin-Higueras C, Salido E, Wang W, Abrams M, Dudek H, Brown BD. Mol Ther. 2018 Aug 1;26(8):1983-1995. PubMed
RNAi-Based GluN3A Silencing Prevents and Reverses Disease Phenotypes Induced by Mutant huntingtin
Marco S, Murillo A, Pérez-Otaño I. Mol Ther. 2018 Aug 1;26(8):1965-1972. PubMed
The Long Noncoding RNA MALAT1 Induces Tolerogenic Dendritic Cells and Regulatory T Cells via miR155/Dendritic Cell-Specific Intercellular Adhesion Molecule-3 Grabbing Nonintegrin/IL10 Axis
Wu J, Zhang H, Zheng Y, Jin X, Liu M, Li S, Zhao Q, Liu X, Wang Y, Shi M, Zhang S, Tian J, Sun Y, Zhang M, Yu B. Front Immunol. 2018 Aug 13;9:1847. PubMed
