DNA Polymerase Variants with High Processivity and Accuracy for Encoding and Decoding Locked Nucleic Acid Sequences
Hoshino H, Kasahara Y, Kuwahara M, Obika S. J Am Chem Soc. 2020 Dec 23;142(51):21530-21537. Pubmed
Enzymatic synthesis of hypermodified DNA polymers for sequence-specific display of four different hydrophobic groups
Ondruš M, Sýkorová V, Bednárová L, Pohl R, Hocek M. Nucleic Acids Res. 2020 Dec 2;48(21):11982-11993. Pubmed
Accelerating Post-SELEX Aptamer Engineering Using Exonuclease Digestion
Canoura J, Yu H, Alkhamis O, Roncancio D, Farhana R, Xiao Y. J Am Chem Soc. 2021 Jan 20;143(2):805-816. Pubmed
Do Aptamers Always Bind? The Need for a Multifaceted Analytical Approach When Demonstrating Binding Affinity between Aptamer and Low Molecular Weight Compounds
Bottari F, Daems E, de Vries AM, Van Wielendaele P, Trashin S, Blust R, Sobott F, Madder A, Martins JC, De Wael K. J Am Chem Soc. 2020 Nov 18;142(46):19622-19630. Pubmed
Assessment of Aptamer-Targeted Contrast Agents for Monitoring of Blood Clots in Computed Tomography and Fluoroscopy Imaging
Koudrina A, O'Brien J, Garcia R, Boisjoli S, Kan PTM, Tsai EC, DeRosa MC. Bioconjug Chem. 2020 Nov 24. Pubmed
Modified aptamers as reagents to characterize recombinant human erythropoietin products
Jankowski W, Lagassé HAD, Chang WC, McGill J, Jankowska KI, Gelinas AD, Janjic N, Sauna ZE. Sci Rep. 2020 Oct 29;10(1):18593. Pubmed
Immunogenicity Assessment of Inotersen, a 2′-O-(2-Methoxyethyl) Antisense Oligonucleotide in Animals and Humans: Effect on Pharmacokinetics, Pharmacodynamics, and Safety
Yu RZ, Wang Y, Norris DA, Kim TW, Narayanan P, Geary RS, Monia BP, Henry SP. Nucleic Acid Ther. 2020 Oct;30(5):265-275. Pubmed
Sensitive fluorescence detection of SARS-CoV-2 RNA in clinical samples via one-pot isothermal ligation and transcription
Woo CH, Jang S, Shin G, Jung GY, Lee JW. Nat Biomed Eng. 2020 Sep 18:1-12. doi: 10.1038/s41551-020-00617-5. Pubmed
Maximizing transcription of nucleic acids with efficient T7 promoters
Conrad T, Plumbom I, Alcobendas M, Vidal R, Sauer S. Commun Biol. 2020 Aug 14;3(1):439. Pubmed
Aptamers against mouse and human tumor-infiltrating myeloid cells as reagents for targeted chemotherapy
De La Fuente A, Zilio S, Caroli J, Van Simaeys D, Mazza EMC, Ince TA, Bronte V, Bicciato S, Weed DT, Serafini P. Sci Transl Med. 2020 Jun 17;12(548):eaav9760. Pubmed
