Circular RNA Immunity

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Presenter: Grace Chen (Yale School of Medicine)

Date: March 25, 2020

Description:

Circular RNAs are a newly appreciated class of ubiquitous and abundant RNAs. In the webinar, we will cover biological and chemical approaches to synthesize circular RNAs, how cells distinguish between endogenous and foreign circular RNAs, and properties of circular RNAs that make it a privileged scaffold for therapeutics. We will address current challenges in the field and future directions.

Recording of the Webinar: Click Play to View

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Prof. Chen would like to make the slides available as there were issues with displaying some of them. Please click here to download and use alongside the talk!

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Presenter Biography

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Grace Chen

Dr. Grace Chen is an Assistant Professor and the Robert T. McCluskey Yale Scholar at Yale University Department of Immunobiology. The Chen Laboratory investigates the diverse functions and mechanisms of endogenous and engineered circular RNAs in health and disease.Dr. Grace Chen obtained a BS in Chemical Biology from the University of California, Berkeley and received her PhD in Chemical Biology from Harvard University, where she worked in Dr. David Liu’s lab studying RNA modifications. Dr. Grace Chen was a postdoctoral fellow with Dr. Howard Chang at Stanford University researching circular RNAs.