Keith Gagnon, Southern Illinois University, USA
Dr. Keith T. Gagnon is an Assistant Professor at Southern Illinois University School of Medicine, USA since 2014 and was elected to the OTS Board of Directors in 2018.
He obtained a BS in Biochemistry (2003) and a PhD in RNA biochemistry (2007) from North Carolina State University. From 2008-2014 he worked as a Post-Doc with Dr. David Corey, where he characterized mechanisms of nuclear RNAi, its necessary cellular machinery and potential for therapeutic application. He also investigated siRNAs and ASOs as therapeutic modalities for repeat expansion disorders, including Huntington’s disease, spinocerebellar ataxia 3, and C9ORF72-associated frontotemporal dementia and amyotrophic lateral sclerosis.
His laboratory focuses on two areas: neurological repeat expansion disorders and RNA-guided enzymes. For the latter, his research focuses on the design, development, and control of CRISPR-based proteins for therapeutic applications, including chemical modification and RNA-protein engineering.