Evolved polymerases facilitate selection of fully 2′-OMe-modified aptamers
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A facile one-step fluorescence method for the quantitation of low-content single base deamination impurity in synthetic oligonucleotides
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Facile Synthesis, Geometry, and 2′-Substituent-Dependent in Vivo Activity of 5′-(E)- and 5′-(Z)-Vinylphosphonate-Modified siRNA Conjugates
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The “Janus face” of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications
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Cholesterol-GalNAc Dual Conjugation Strategy for Reducing Renal Distribution of Antisense Oligonucleotides
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Structural properties and gene-silencing activity of chemically modified DNA-RNA hybrids with parallel orientation
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Modulation of BACE1 activity by chemically modified aptamers
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