A Mechanism for microRNA Arm Switching Regulated by Uridylation
Kim H, Kim J, Yu S, Lee YY, Park J, Choi RJ, Yoon SJ, Kang SG, Kim VN. Mol Cell. 2020 May 12:S1097-2765(20)30272-0. Pubmed
Base-pair conformational switch modulates miR-34a targeting of Sirt1 mRNA
Baronti L, Guzzetti I, Ebrahimi P, Friebe Sandoz S, Steiner E, Schlagnitweit J, Fromm B, Silva L, Fontana C, Chen AA, Petzold K. Nature. 2020 May 27. Pubmed
Development of an RNAi therapeutic for alpha-1-antitrypsin liver disease
Wooddell CI, Blomenkamp K, Peterson RM, Subbotin VM, Schwabe C, Hamilton J, Chu Q, Christianson DR, Hegge JO, Kolbe J, Hamilton HL, Branca-Afrazi MF, Given BD, Lewis DL, Gane E, Kanner SB, Teckman JH. JCI Insight. 2020 May 7:135348. Pubmed
Selective Naked-Eye Detection of SARS-CoV-2 Mediated by N Gene Targeted Antisense Oligonucleotide Capped Plasmonic Nanoparticles
Moitra P, Alafeef M, Dighe K, Frieman M, Pan D. ACS Nano. 2020 May 28:acsnano.0c03822. Pubmed
Oligonucleotide Therapeutics: New Drugs That Could Stop COVID-19
In response to the COVID-19 pandemic, scientists around the world have joined together in applying their skills and technologies to fight this global threat. Some of the most promising technologies to fight the coronavirus are based on a new type of drug called oligonucleotide ...