Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer’s disease
Baker SK, Chen ZL, Norris EH, Revenko AS, MacLeod AR, Strickland S. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9687-E9696. PubMed
Huntingtin suppression restores cognitive function in a mouse model of Huntington’s disease
Southwell AL, Kordasiewicz HB, Langbehn D, Skotte NH, Parsons MP, Villanueva EB, Caron NS, Ă˜stergaard ME, Anderson LM, Xie Y, Cengio LD, Findlay-Black H, Doty CN, Fitsimmons B, Swayze EE, Seth PP, Raymond LA, Frank Bennett C, Hayden MR. Sci Transl Med. 2018 Oct 3;10(461). ...
Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7
Niu C, Prakash TP, Kim A, Quach JL, Huryn LA, Yang Y, Lopez E, Jazayeri A, Hung G, Sopher BL, Brooks BP, Swayze EE, Bennett CF, La Spada AR. Sci Transl Med. 2018 Oct 31;10(465). PubMed
Loss of hepatocyte β-Catenin protects mice from experimental porphyria-associated liver injury
Saggi H, Maitra D, Jiang A, Zhang R, Wang P, Cornuet P, Singh S, Locker J, Ma X, Dailey H, Abrams M, Omary MB, Monga SP, Nejak-Bowen K. J Hepatol. 2018 Oct 1. pii: S0168-8278(18)32442-5. PubMed
Reducing dynamin 2 (DNM2) rescues DNM2-related dominant centronuclear myopathy
Buono S, Ross JA, Tasfaout H, Levy Y, Kretz C, Tayefeh L, Matson J, Guo S, Kessler P, Monia BP, Bitoun M, Ochala J, Laporte J, Cowling BS. Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):11066-11071. PubMed
LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis
Zhu P, Wu J, Wang Y, Zhu X, Lu T, Liu B, He L, Ye B, Wang S, Meng S, Fan D, Wang J, Yang L, Qin X, Du Y, Li C, He L, Ren W, Wu X, Tian Y, Fan Z. Nat Cell Biol. ...
The cisplatin-induced lncRNA PANDAR dictates the chemoresistance of ovarian cancer via regulating SFRS2-mediated p53 phosphorylation
Wang H, Fang L, Jiang J, Kuang Y, Wang B, Shang X, Han P, Li Y, Liu M, Zhang Z, Li P. Cell Death Dis. 2018 Oct 30;9(11):1103. PubMed
MicroRNA-23a-5p promotes atherosclerotic plaque progression and vulnerability by repressing ATP-binding cassette transporter A1/G1 in macrophages
Yang S, Ye ZM, Chen S, Luo XY, Chen SL, Mao L, Li Y, Jin H, Yu C, Xiang FX, Xie MX, Chang J, Xia YP, Hu B. J Mol Cell Cardiol. 2018 Oct;123:139-149. PubMed
MicroRNA-27a controls the intracellular survival of Mycobacterium tuberculosis by regulating calcium-associated autophagy
Liu F, Chen J, Wang P, Li H, Zhou Y, Liu H, Liu Z, Zheng R, Wang L, Yang H, Cui Z, Wang F, Huang X, Wang J, Sha W, Xiao H, Ge B. Nat Commun. 2018 Oct 16;9(1):4295. PubMed
microRNA-181a-5p antisense oligonucleotides attenuate osteoarthritis in facet and knee joints
Nakamura A, Rampersaud YR, Nakamura S, Sharma A, Zeng F, Rossomacha E, Ali SA, Krawetz R, Haroon N, Perruccio AV, Mahomed NN, Gandhi R, Rockel JS, Kapoor M. Ann Rheum Dis. 2018 Oct 4. PubMed