The chemical structure and phosphorothioate content of hydrophobically modified siRNAs impact extrahepatic distribution and efficacy. - Oligonucleotide Therapeutics Society

The chemical structure and phosphorothioate content of hydrophobically modified siRNAs impact extrahepatic distribution and efficacy.

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OTS

DATE

August 5, 2020

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Ago/siRNA/saRNA

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Biscans A, Caiazzi J, Davis S, McHugh N, Sousa J, Khvorova A.

Nucleic Acids Res. 2020 Jul 16

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