High-throughput identification of synthetic riboswitches by barcode-free amplicon-sequencing in human cells

AUTHOR

OTS

DATE

February 29, 2020

CATEGORIES

Ribozyme

Post Views: 288

Strobel B, Spöring M, Klein H, Blazevic D, Rust W, Sayols S, Hartig JS, Kreuz S.
Nat Commun. 2020 Feb 5;11(1):714.

PubMed

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High-throughput identification of synthetic riboswitches by barcode-free amplicon-sequencing in human cells

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High-throughput identification of synthetic riboswitches by barcode-free amplicon-sequencing in human cells

Related articles

Targeted suicide gene therapy for liver cancer based on ribozyme-mediated RNA replacement through post-transcriptional regulation

Hovlinc is a recently evolved class of ribozyme found in human lncRNA

siRNAs containing 2′-fluorinated Northern-methanocarbacyclic (2′-F-NMC) nucleotides: in vitro and in vivo RNAi activity and inability of mitochondrial polymerases to incorporate 2′-F-NMC NTPs

Perspectives on the Designation of Oligonucleotide Starting Materials

Site-specific incorporation of 5′-methyl DNA enhances the therapeutic profile of gapmer ASOs.

Replacement of L-amino acid peptides with D-amino acid peptides mitigates anti-PEG antibody generation against polymer-peptide conjugates in mice

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