Directed evolution of adenine base editors with increased activity and therapeutic application

Gaudelli NM, Lam DK, Rees HA, Solá-Esteves NM, Barrera LA, Born DA, Edwards A, Gehrke JM, Lee SJ, Liquori AJ, Murray R, Packer MS, Rinaldi C, Slaymaker IM, Yen J, Young LE, Ciaramella G.
Nat Biotechnol. 2020 Apr 13.

PubMed