Time: 5pm Amsterdam
Date: April 13, 2023
Topics/Speakers:
Oligo-PROTAC strategy for cell-selective and targeted degradation of activated STAT3
Jeremy Hall
City of Hope & Keck Graduate Institute
Jeremy will present a summary of the research that outlines how the mechanism of this Oligo-PROTAC was illustrated, along with recent data demonstrating immunoregulatory effects of targeting STAT3, and should they be successful, updated in vivo data.
Triblock Heterochiral Oligonucleotide Nanotechnology
Tracy L. Mallette
University of New Mexico
Tracy will present on using triblock, heterochiral L- and D-DNA strands in a strand displacement based molecular circuits to resist exonuclease-mediated degradation during extended incubations
