Quantification Methods
Categories: Past WebinarsPublished On: September 29th, 2019


Quantification Methods

Presenter: Mai Thayer, Amgen, USA

Date: October 8, 2019


Oligonucleotides are a quickly evolving modality with strong proof of concept established in the clinic. Despite the clinical success of oligonucleotides, there is still limited understanding of ADME (absorption, disposition, metabolism and excretion) in comparison to other modalities (e.g. small molecules). The presentation will discuss the current strategies to effectively characterize oligonucleotides from early discovery into the clinical setting by discussing novel, robust, and sensitive bioanalytical tools enabling measurement of oligonucleotides in blood and tissues.

Recording of the Webinar: Click Play to View

Presenter Biography

Mai Thayer, Amgen, USA

Mai Thayer holds a Bachelor of Science degree in biochemistry and molecular biology from University of California, Davis, and a Master degree of Science in Pharmaceutical Bioengineering from the University of Washington. She has extensive experience working on teams to develop the next generations of therapeutics, including small molecules, antibodies, and RNAi molecules, and currently works within the Pharmacokinetic and Drug Metabolism group at Amgen Research in South San Francisco, CA.