Research Scientist

Research Scientist

Full time @Western Washington University in General
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Job Detail

  • Job Type Full-time
  • Industry General

Job Description

Work in the Carroll lab is focused on understanding whole body symptoms of Huntington’s disease using genetic mouse models. We are particularly interested in the role that brain-body cross talk plays in the development of HD symptoms. Dr. Carroll is also engaged in education efforts targeting the Huntington’s disease community, including HD Buzz, and the effects these educational efforts have on community member’s decision making.

In the Carroll lab, the research scientist will use established protocols to isolate and conduct ASO-based experiments in Huntington’s disease model mice to study the relationship between huntingtin lowering and pathological signs of Huntington’s disease.

These projects will require both surgical and molecular biology expertise, including stereotaxic and retro-orbital injections, genotyping of mice by polymerase chain reaction (PCR), quantifying levels of proteins and RNA using western blots and quantitative real-time PCR, various microplate reader-based assays and confocal immunohistochemistry.

The job will also include significant in vitro experiments using administration of stressor compounds to primary neurons, to examine the impact of silencing the huntingtin gene on specific stress response pathways.

Required Qualifications
Bachelor’s degree or higher in biology, neurobiology, or a related field
Laboratory mouse experience, including survival surgeries
Full-time laboratory experience, either post-graduation or during advanced training
Experience with computational data analysis (e.g. R, Python, Matlab, Prism, SPSS)
Demonstrated commitment to cultivating a work environment that is equitable and inclusive of faculty, staff, and students from diverse cultural backgrounds and social identities.

Preferred Qualifications
Advanced degree (MS, PhD or related degree)
Experience with independently planning and managing large-scale mouse experiments
Laboratory Mouse Experience, including: stereotaxic injections, peripheral injections (IP, SubQ, IV and retro-orbital)
Tissue culture experience, including primary cell culture
Molecular Biology Experience: Including polymerase chain reaction-based genotyping, plate-reader based assays and gene expression analysis with QRT-PCR, microarrays and/or RNA sequencing
Strong interpersonal communication skills

Western Washington University, with over 16,000 students in seven colleges and the graduate school, is nationally recognized for its educational programs, students and faculty. The campus is located in Bellingham, Washington, a coastal community of 90,000 overlooking Bellingham Bay, the San Juan Islands and the North Cascades Mountain range. The city lies 90 miles north of Seattle and 60 miles south of Vancouver, British Columbia. Western is the highest-ranking public, master’s-granting university in the Pacific Northwest, according to the 2019 U.S. News & World Report rankings.

The College of Humanities and Social Sciences and the Psychology Department support Western’s mission, which states that together with our students, staff, and faculty, we are committed to making a positive impact in the state and the world with a shared focus on academic excellence and inclusive achievement. We encourage applications from women, people of color, people with disabilities, veterans, and other candidates from underrepresented backgrounds and with diverse experiences interested in this opportunity.

New hires typically begin at $64,997- $75,829, commensurate with experience; Includes an excellent benefits package.
Application review begins November 30, 2021; position is open until filled.

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