Nucleic Acid Therapeutics Initiative

The Nucleic Acid Therapeutics Initiative (NATi), hosted by A*STAR, is Singapore’s national platform dedicated to advancing RNA-based medicines and revolutionizing drug and vaccine development. NATi’s mission is to establish Singapore as a globally recognized hub of excellence in nucleic acid therapeutics research, clinical translation, and commercialization.

NATi focuses on key RNA modalities such as antisense oligonucleotides (ASOs), small interfering RNA (siRNA), and messenger RNA (mRNA). To drive this vision, NATi is building a biotech-like translational engine focused on asset and technology development spanning discovery to clinical development.

We are actively seeking passionate and committed RNA scientists with deep translational expertise to join us in advancing the next generation of RNA-based therapeutics.