Intracellular delivery of therapeutic antisense oligonucleotides targeting mRNA coding mitochondrial proteins by cell-penetrating peptides
Cerrato CP, Kivijärvi T, Tozzi R, Lehto T, Gestin M, Langel Ăœ. J Mater Chem B. 2020 Epub 2020 Nov 11. Pubmed
Do Aptamers Always Bind? The Need for a Multifaceted Analytical Approach When Demonstrating Binding Affinity between Aptamer and Low Molecular Weight Compounds
Bottari F, Daems E, de Vries AM, Van Wielendaele P, Trashin S, Blust R, Sobott F, Madder A, Martins JC, De Wael K. J Am Chem Soc. 2020 Nov 18;142(46):19622-19630. Pubmed
Assessment of Aptamer-Targeted Contrast Agents for Monitoring of Blood Clots in Computed Tomography and Fluoroscopy Imaging
Koudrina A, O'Brien J, Garcia R, Boisjoli S, Kan PTM, Tsai EC, DeRosa MC. Bioconjug Chem. 2020 Nov 24. Pubmed
Poison Exon Splicing Regulates a Coordinated Network of SR Protein Expression during Differentiation and Tumorigenesis
Leclair NK, Brugiolo M, Urbanski L, Lawson SC, Thakar K, Yurieva M, George J, Hinson JT, Cheng A, Graveley BR, AnczukĂ³w O. Mol Cell. 2020 Nov 19;80(4):648-665.e9. Pubmed
Efficient Gene Suppression by DNA/DNA Double-Stranded Oligonucleotide In Vivo
Asami Y, Nagata T, Yoshioka K, Kunieda T, Yoshida-Tanaka K, Bennett CF, Seth PP, Yokota T. Mol Ther. 2020 Nov 25:S1525-0016(20)30551-7. Pubmed
Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis
Shen M, Xie S, Rowicki M, Michel S, Wei Y, Hang X, Wan L, Lu X, Yuan M, Jin JF, Jaschinski F, Zhou T, Klar R, Kang Y. Cancer Res. 2020 Nov 25:canres.1876.2020. Pubmed
Modified aptamers as reagents to characterize recombinant human erythropoietin products
Jankowski W, Lagassé HAD, Chang WC, McGill J, Jankowska KI, Gelinas AD, Janjic N, Sauna ZE. Sci Rep. 2020 Oct 29;10(1):18593. Pubmed
Determination of isoform-specific RNA structure with nanopore long reads
Aw JGA, Lim SW, Wang JX, Lambert FRP, Tan WT, Shen Y, Zhang Y, Kaewsapsak P, Li C, Ng SB, Vardy LA, Tan MH, Nagarajan N, Wan Y. Nat Biotechnol. 2020 Oct 26 Pubmed
COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses
Sahin U, Muik A, Derhovanessian E, Vogler I, Kranz LM, Vormehr M, Baum A, Pascal K, Quandt J, Maurus D, Brachtendorf S, Lörks V, Sikorski J, Hilker R, Becker D, Eller AK, GrĂ¼tzner J, Boesler C, Rosenbaum C, KĂ¼hnle MC, Luxemburger U, Kemmer-BrĂ¼ck A, Langer ...
Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates
Walsh EE, Frenck RW Jr, Falsey AR, Kitchin N, Absalon J, Gurtman A, Lockhart S, Neuzil K, Mulligan MJ, Bailey R, Swanson KA, Li P, Koury K, Kalina W, Cooper D, Fontes-Garfias C, Shi PY, TĂ¼reci Ă–, Tompkins KR, Lyke KE, Raabe V, Dormitzer PR, ...