A strongly pairing fifth base: oligonucleotides with a C-nucleoside replacing thymidine
Walter TJ, Richert C. Nucleic Acids Res. 2018 Sep 19;46(16):8069-8078. PubMed
Exosome-Mediated Small RNA Delivery: A Novel Therapeutic Approach for Inflammatory Lung Responses
Zhang D, Lee H, Wang X, Rai A, Groot M, Jin Y. Mol Ther. 2018 Sep 5;26(9):2119-2130. PubMed
Intratracheal Administration of siRNA Dry Powder Targeting Vascular Endothelial Growth Factor Inhibits Lung Tumor Growth in Mice
Miwata K, Okamoto H, Nakashima T, Ihara D, Horimasu Y, Masuda T, Miyamoto S, Iwamoto H, Fujitaka K, Hamada H, Shibata A, Ito T, Okuda T, Hattori N. Mol Ther Nucleic Acids. 2018 Sep 7;12:698-706. PubMed
Inhaled TLR9 Agonist Renders Lung Tumors Permissive to PD-1 Blockade by Promoting Optimal CD4+ and CD8+ T-cell Interplay
Gallotta M, Assi H, Degagné É, Kannan SK, Coffman RL, Guiducci C. Cancer Res. 2018 Sep 1;78(17):4943-4956. PubMed
A synthetic microRNA-92a inhibitor (MRG-110) accelerates angiogenesis and wound healing in diabetic and nondiabetic wounds
Gallant-Behm CL, Piper J, Dickinson BA, Dalby CM, Pestano LA, Jackson AL. Wound Repair Regen. 2018 Aug 17. PubMed
Hepatic-targeted RNA interference provides robust and persistent knockdown of alpha-1 antitrypsin levels in ZZ patients
Turner AM, Stolk J, Bals R, Lickliter JD, Hamilton J, Christianson DR, Given BD, Burdon JG, Loomba R, Stoller JK, Teckman JH. J Hepatol. 2018 Aug;69(2):378-384. PubMed
COMRADES determines in vivo RNA structures and interactions
Ziv O, Gabryelska MM, Lun ATL, Gebert LFR, Sheu-Gruttadauria J, Meredith LW, Liu ZY, Kwok CK, Qin CF, MacRae IJ, Goodfellow I, Marioni JC, Kudla G, Miska EA. Nat Methods. 2018 Sep 10. PubMed
Structural optimization of pseudorotaxane-forming oligonucleotides for efficient and stable complex formation
Onizuka K, Miyashita T, Chikuni T, Ozawa M, Abe H, Nagatsugi F. Nucleic Acids Res. 2018 Sep 28;46(17):8710-8719. PubMed
Nuclear Localization of Huntingtin mRNA Is Specific to Cells of Neuronal Origin
Didiot MC, Ferguson CM, Ly S, Coles AH, Smith AO, Bicknell AA, Hall LM, Sapp E, Echeverria D, Pai AA, DiFiglia M, Moore MJ, Hayward LJ, Aronin N, Khvorova A. Cell Rep. 2018 Sep 4;24(10):2553-2560.e5. PubMed
Increased Frataxin Expression Induced in Friedreich Ataxia Cells by Platinum TALE-VP64s or Platinum TALE-SunTag
Cherif K, GĂ©rard C, Rousseau J, Ouellet DL, Chapdelaine P, Tremblay JP. Mol Ther Nucleic Acids. 2018 Sep 7;12:19-32. PubMed