A DNA origami-based aptamer nanoarray for potent and reversible anticoagulation in hemodialysis
Zhao S, Tian R, Wu J, Liu S, Wang Y, Wen M, Shang Y, Liu Q, Li Y, Guo Y, Wang Z, Wang T, Zhao Y, Zhao H, Cao H, Su Y, Sun J, Jiang Q, Ding B. Nat Commun. 2021 Jan 13;12(1):358. Pubmed ...
In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice
Koblan LW, Erdos MR, Wilson C, Cabral WA, Levy JM, Xiong ZM, Tavarez UL, Davison LM, Gete YG, Mao X, Newby GA, Doherty SP, Narisu N, Sheng Q, Krilow C, Lin CY, Gordon LB, Cao K, Collins FS, Brown JD, Liu DR. Nature. 2021 Jan;589(7843):608-614. ...
iR-10b-5p Rescues Diabetes and Gastrointestinal Dysmotility
Singh R, Ha SE, Wei L, Jin B, Zogg H, Poudrier SM, Jorgensen BG, Park C, Ronkon CF, Bartlett A, Cho S, Morales A, Chung YH, Lee MY, Park JK, Gottfried-Blackmore A, Nguyen L, Sanders KM, Ro S. Gastroenterology. 2021 Jan 7:S0016-5085(21)00001-9. Pubmed ...
Endothelial-Derived miR-17∼92 Promotes Angiogenesis to Protect against Renal Ischemia-Reperfusion Injury
Chiba T, Cerqueira DM, Li Y, Bodnar AJ, Mukherjee E, Pfister K, Phua YL, Shaikh K, Sanders BT, Hemker SL, Pagano PJ, Wu YL, Ho J, Sims-Lucas S. J Am Soc Nephrol. 2021 Jan 29:ASN.2020050717. Pubmed
Renal AAV2-Mediated Overexpression of Long Non-Coding RNA H19 Attenuates Ischemic Acute Kidney Injury Through Sponging of microRNA-30a-5p.
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Targeting the 5′ untranslated region of SMN2 as a therapeutic strategy for spinal muscular atrophy
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Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption
Mondala PK, Vora AA, Zhou T, Lazzari E, Ladel L, Luo X, Kim Y, Costello C, MacLeod AR, Jamieson CHM, Crews LA. Cell Stem Cell. 2021 Jan 20:S1934-5909(20)30601-9. Pubmed
Clinical Pharmacology Studies Supporting Oligonucleotide Therapy Development: An Assessment of Therapies Approved and in Development Between 2012-2018
Rogers H, Adeniyi O, Ramamoorthy A, Bailey S, Pacanowski M. Clin Transl Sci. 2020 Dec 5. Pubmed
RNA structure-wide discovery of functional interactions with multiplexed RNA motif library
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Functional Atlas of Primary miRNA Maturation by the Microprocessor
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