Determination of RNA structural diversity and its role in HIV-1 RNA splicing
Tomezsko PJ, Corbin VDA, Gupta P, Swaminathan H, Glasgow M, Persad S, Edwards MD, Mcintosh L, Papenfuss AT, Emery A, Swanstrom R, Zang T, Lan TCT, Bieniasz P, Kuritzkes DR, Tsibris A, Rouskin S. Nature. 2020 Jun;582(7812):438-442. Pubmed
Engineered Circular RNA Sponges Act as miRNA Inhibitors to Attenuate Pressure Overload-Induced Cardiac Hypertrophy
Lavenniah A, Luu TDA, Li YP, Lim TB, Jiang J, Ackers-Johnson M, Foo RS. Mol Ther. 2020 Jun 3;28(6):1506-1517. Pubmed
Novel antisense inhibition of diacylglycerol O-acyltransferase 2 for treatment of non-alcoholic fatty liver disease: a multicentre, double-blind, randomised, placebo-controlled phase 2 trial
Loomba R, Morgan E, Watts L, Xia S, Hannan LA, Geary RS, Baker BF, Bhanot S. Lancet Gastroenterol Hepatol. 2020 Jun 15:S2468-1253(20)30186-2. Pubmed
Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria
Balwani M, Sardh E, Ventura P, PeirĂ³ PA, Rees DC, Stölzel U, Bissell DM, Bonkovsky HL, Windyga J, Anderson KE, Parker C, Silver SM, Keel SB, Wang JD, Stein PE, Harper P, Vassiliou D, Wang B, Phillips J, Ivanova A, Langendonk JG, Kauppinen R, Minder ...
POE Immunoassay: Plate-based oligonucleotide electro-chemiluminescent immunoassay for the quantification of nucleic acids in biological matrices
Thayer MB, Humphreys SC, Chung KS, Lade JM, Cook KD, Rock BM. Sci Rep. 2020 Jun 26;10(1):10425. Pubmed
Dose-Finding Study and Pharmacokinetics Profile of the Novel 13-Mer Antisense miR-221 Inhibitor in Sprague-Dawley Rats
Di Martino MT, Arbitrio M, Caracciolo D, Scionti F, Tagliaferri P, Tassone P. Mol Ther Nucleic Acids. 2020 Jun 5;20:73-85. Pubmed
Rational design of antisense oligonucleotides modulating the activity of TLR7/8 agonists
Alharbi AS, Garcin AJ, Lennox KA, Pradeloux S, Wong C, Straub S, Valentin R, PĂ©pin G, Li HM, Nold MF, Nold-Petry CA, Behlke MA, Gantier MP. Nucleic Acids Res. 2020 Jun 16:gkaa523. Pubmed
Nanoparticle delivery of immunostimulatory oligonucleotides enhances response to checkpoint inhibitor therapeutics.
Buss CG, Bhatia SN. Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13428-13436. Pubmed
Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing
Wei T, Cheng Q, Min YL, Olson EN, Siegwart DJ. Nat Commun. 2020 Jun 26;11(1):3232. Pubmed
Defining the Design Parameters for in Vivo Enzyme Delivery Through Protein Spherical Nucleic Acids
Kusmierz CD, Bujold KE, Callmann CE, Mirkin CA. ACS Cent Sci. 2020 May 27;6(5):815-822. Pubmed