Engineered Circular RNA Sponges Act as miRNA Inhibitors to Attenuate Pressure Overload-Induced Cardiac Hypertrophy
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Amplified Self-Immolative Release of Small Molecules by Spatial Isolation of Reactive Groups on DNA-Minimal Architectures
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Structural disruption of exonic stem-loops immediately upstream of the intron regulates mammalian splicing
Saha K, England W, Fernandez MM, Biswas T, Spitale RC, Ghosh G. Nucleic Acids Res. 2020 May 13:gkaa358. Pubmed
Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair
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Big Is Beautiful: Enhanced saRNA Delivery and Immunogenicity by a Higher Molecular Weight, Bioreducible, Cationic Polymer
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Treatment of Hemophilia A Using Factor VIII Messenger RNA Lipid Nanoparticles
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Engineering Caveolae-Targeted Lipid Nanoparticles To Deliver mRNA to the Lungs
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Aerosol Delivery of Synthetic mRNA to Vaginal Mucosa Leads to Durable Expression of Broadly Neutralizing Antibodies against HIV
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A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA
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Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA
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