Overexpression of miRNA-137 in the brain suppresses seizure activity and neuronal excitability: A new potential therapeutic strategy for epilepsy
Wang W, Guo Y, He L, Chen C, Luo J, Ma Y, Li J, Yang Y, Yang Q, Du C, Zhang Y, Li Z, Xu X, Tian X, Wang X. Neuropharmacology. 2018 Jun 9;138:170-181. PubMed
Cryptotanshinone Protects Cartilage against Developing Osteoarthritis through the miR-106a-5p/GLIS3 Axis
Ji Q, Qi D, Xu X, Xu Y, Goodman SB, Kang L, Song Q, Fan Z, Maloney WJ, Wang Y. Mol Ther Nucleic Acids. 2018 Jun 1;11:170-179. PubMed
miR-23b and miR-218 silencing increase Muscleblind-like expression and alleviate myotonic dystrophy phenotypes in mammalian models
Cerro-Herreros E, Sabater-Arcis M, Fernandez-Costa JM, Moreno N, Perez-Alonso M, Llamusi B, Artero R. Nat Commun. 2018 Jun 26;9(1):2482. PubMed
MicroRNA-351-5p aggravates intestinal ischemia/reperfusion injury via targeting MAPK13 and Sirt6
Hu Y, Tao X, Han X, Xu L, Yin L, Sun H, Qi Y, Xu Y, Peng J. Br J Pharmacol. 2018 Jun 27. PubMed
Effects of microRNA-292-5p on myocardial ischemia-reperfusion injury through the peroxisome proliferator-activated receptor-α/-γ signaling pathway
Zhu ZD, Ye JY, Niu H, Ma YM, Fu XM, Xia ZH, Zhang X. Gene Ther. 2018 Jun;25(3):234-248. PubMed
Artificial miRNAs Reduce Human Mutant Huntingtin Throughout the Striatum in a Transgenic Sheep Model of Huntington’s Disease
Pfister EL, DiNardo N, Mondo E, Borel F, Conroy F, Fraser C, Gernoux G, Han X, Hu D, Johnson E, Kennington L, Liu P, Reid SJ, Sapp E, Vodicka P, Kuchel T, Morton AJ, Howland D, Moser R, Sena-Esteves M, Gao G, Mueller C, DiFiglia ...
A dual-targeting reconstituted high density lipoprotein leveraging the synergy of sorafenib and antimiRNA21 for enhanced hepatocellular carcinoma therapy
Li M, Su Y, Zhang F, Chen K, Xu X, Xu L, Zhou J, Wang W. Acta Biomater. 2018 May 31. pii: S1742-7061(18)30328-3. PubMed
miR-223-3p Inhibits Human Osteosarcoma Metastasis and Progression by Directly Targeting CDH6
Ji Q, Xu X, Song Q, Xu Y, Tai Y, Goodman SB, Bi W, Xu M, Jiao S, Maloney WJ, Wang Y. Mol Ther. 2018 May 2;26(5):1299-1312. PubMed
The microRNA-371~373 cluster represses colon cancer initiation and metastatic colonization by inhibiting the TGFBR2/ID1 signaling axis
Ullmann P, Rodriguez F, Schmitz M, Meurer SK, Qureshi-Baig K, Felten P, Ginolhac A, Antunes L, Frasquilho S, ZĂ¼gel N, Weiskirchen R, Haan S, Letellier E. Cancer Res. 2018 May 10. pii: canres.3003.2017. PubMed
MicroRNAs as potential therapeutics to enhance chemosensitivity in advanced prostate cancer
Lin HM, Nikolic I, Yang J, Castillo L, Deng N, Chan CL, Yeung NK, Dodson E, Elsworth B, Spielman C, Lee BY, Boyer Z, Simpson KJ, Daly RJ, Horvath LG, Swarbrick A. Sci Rep. 2018 May 18;8(1):7820. PubMed