Aerosol Delivery of Synthetic mRNA to Vaginal Mucosa Leads to Durable Expression of Broadly Neutralizing Antibodies against HIV
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Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA
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Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood-brain barrier
Marcos-Contreras OA, Greineder CF, Kiseleva RY, Parhiz H, Walsh LR, Zuluaga-Ramirez V, Myerson JW, Hood ED, Villa CH, Tombacz I, Pardi N, Seliga A, Mui BL, Tam YK, Glassman PM, Shuvaev VV, Nong J, Brenner JS, Khoshnejad M, Madden T, Weissmann D, Persidsky Y, Muzykantov ...
Sequence Multiplicity within Spherical Nucleic Acids.
Huang ZN, Cole LE, Callmann CE, Wang S, Mirkin CA. ACS Nano. 2020 Jan 28;14(1):1084-1092. PubMed
Systemic Brain Delivery of Antisense Oligonucleotides across the Blood-Brain Barrier with a Glucose-Installed Polymeric Nanocarrier.
Min HS, Kim HJ, Naito M, Ogura S, Toh K, Hayashi K, Kim BS, Fukushima S, Anraku Y, Miyata K, Kataoka K. Angew Chem Int Ed Engl. 2020 Jan 29. PubMed
Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation.
Yang Z, Shi J, Xie J, Wang Y, Sun J, Liu T, Zhao Y, Zhao X, Wang X, Ma Y, Malkoc V, Chiang C, Deng W, Chen Y, Fu Y, Kwak KJ, Fan Y, Kang C, Yin C, Rhee J, Bertani P, Otero J, Lu ...
The effector mechanism of siRNA spherical nucleic acids.
Yamankurt G, Stawicki RJ, Posadas DM, Nguyen JQ, Carthew RW, Mirkin CA. Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1312-1320. PubMed
HER3-targeted protein chimera forms endosomolytic capsomeres and self-assembles into stealth nucleocapsids for systemic tumor homing of RNA interference in vivo.
Alonso-Valenteen F, Pacheco S, Srinivas D, Rentsendorj A, Chu D, Lubow J, Sims J, Miao T, Mikhael S, Hwang JY, Abrol R, Medina Kauwe LK. Nucleic Acids Res. 2019 Dec 2;47(21):11020-11043. PubMed
A Sendai Virus-Based Cytoplasmic RNA Vector as a Novel Platform for Long-Term Expression of MicroRNAs.
Sano M, Nakasu A, Ohtaka M, Nakanishi M. Mol Ther Methods Clin Dev. 2019 Oct 31;15:371-382. PubMed
Hydrophobically Modified let-7b miRNA Enhances Biodistribution to NSCLC and Downregulates HMGA2 In Vivo.
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