A Chymase Inhibitory RNA Aptamer Improves Cardiac Function and Survival after Myocardial Infarction
Jin D, Takai S, Nonaka Y, Yamazaki S, Fujiwara M, Nakamura Y. Mol Ther Nucleic Acids. 2019 Mar 1;14:41-51. PubMed
Genetic Alphabet Expansion Provides Versatile Specificities and Activities of Unnatural-Base DNA Aptamers Targeting Cancer Cells
Futami K, Kimoto M, Lim YWS, Hirao I. Mol Ther Nucleic Acids. 2019 Mar 1;14:158-170. PubMed
Hachimoji DNA and RNA: A genetic system with eight building blocks
Hoshika S, Leal NA, Kim MJ, Kim MS, Karalkar NB, Kim HJ, Bates AM, Watkins NE Jr, SantaLucia HA, Meyer AJ, DasGupta S, Piccirilli JA, Ellington AD, SantaLucia J Jr, Georgiadis MM, Benner SA. Science. 2019 Feb 22;363(6429):884-887. PubMed
RNA inhibitors of nuclear proteins responsible for multiple organ dysfunction syndrome
Urak KT, Blanco GN, Shubham S, Lin LH, Dassie JP, Thiel WH, Chen Y, Sonkar VK, Lei B, Murthy S, Gutierrez WR, Wilson ME, Stiber JA, Klesney-Tait J, Dayal S, Miller FJ Jr, Giangrande PH. Nat Commun. 2019 Jan 10;10(1):116. PubMed
Treating Tumors at Low Drug Doses Using an Aptamer-Peptide Synergistic Drug Conjugate
Pusuluri A, Krishnan V, Lensch V, Sarode A, Bunyan E, Vogus DR, Menegatti S, Soh HT, Mitragotri S. Angew Chem Int Ed Engl. 2019 Jan 28;58(5):1437-1441. PubMed
Bioinspired Engineering of a Multivalent Aptamer-Functionalized Nanointerface to Enhance the Capture and Release of Circulating Tumor Cells
Song Y, Shi Y, Huang M, Wang W, Wang Y, Cheng J, Lei Z, Zhu Z, Yang C. Angew Chem Int Ed Engl. 2018 Dec 13. PubMed
Poly-Target Selection Identifies Broad-Spectrum RNA Aptamers
Alam KK, Chang JL, Lange MJ, Nguyen PDM, Sawyer AW, Burke DH. Mol Ther Nucleic Acids. 2018 Dec 7;13:605-619. PubMed
Phosphorothioate-Modified AP613-1 Specifically Targets GPC3 when Used for Hepatocellular Carcinoma Cell Imaging
Dong L, Zhou H, Zhao M, Gao X, Liu Y, Liu D, Guo W, Hu H, Xie Q, Fan J, Lin J, Wu W. Mol Ther Nucleic Acids. 2018 Dec 7;13:376-386. PubMed
Activation of Innate Immune Responses by a Cytosine-Phosphate-Guanine Oligonucleotide Sequence Composed Entirely of Threose Nucleic Acid
Lange MJ, Burke DH, Chaput JC. Nucleic Acid Ther. 2018 Dec 11. PubMed
Tethered imidazole mediated duplex stabilization and its potential for aptamer stabilization
Verdonck L, Buyst D, de Vries AM, Gheerardijn V, Madder A, Martins JC. Nucleic Acids Res. 2018 Nov 10. PubMed