Nuclear miR-320 Mediates Diabetes-Induced Cardiac Dysfunction by Activating Transcription of Fatty Acid Metabolic Genes to Cause Lipotoxicity in the Heart
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The role of apolipoprotein- and vitronectin-enriched protein corona on lipid nanoparticles for in vivo targeted delivery and transfection of oligonucleotides in murine tumor models
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Ligand Conjugated Multimeric siRNAs Enable Enhanced Uptake and Multiplexed Gene Silencing
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Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide
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Plasma and Liver Protein Binding of N-Acetylgalactosamine-Conjugated Small Interfering RNA
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Suppression of Choroidal Neovascularization and Fibrosis by a Novel RNAi Therapeutic Agent against (Pro)renin Receptor
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Targeted Delivery of C/EBPα-saRNA by RNA Aptamers Shows Anti-tumor Effects in a Mouse Model of Advanced PDAC
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A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system
Alterman JF, Godinho BMDC, Hassler MR, Ferguson CM, Echeverria D, Sapp E, Haraszti RA, Coles AH, Conroy F, Miller R, Roux L, Yan P, Knox EG, Turanov AA, King RM, Gernoux G, Mueller C, Gray-Edwards HL, Moser RP, Bishop NC, Jaber SM, Gounis MJ, Sena-Esteves ...
Constrained Nanoparticles Deliver siRNA and sgRNA to T Cells In Vivo without Targeting Ligands
Lokugamage MP, Sago CD, Gan Z, Krupczak BR, Dahlman JE. Adv Mater. 2019 Aug 29:e1902251. PubMed
Reactive modifications of DNA nucleobases for labelling, bioconjugations, and cross-linking
IvancovĂ¡ I, Leone DL, Hocek M. Curr Opin Chem Biol. 2019 Aug 12;52:136-144. PubMed