Imaging small molecule-induced endosomal escape of siRNA

Paper of the Month: Imaging small molecule-induced endosomal escape of siRNA …………… Du Rietz H, Hedlund H, Wilhelmson S, Nordenfelt P, Wittrup A. Nat Commun. 2020 Apr 14;11(1):1809.   Hampus Du Rietz and Dr. Anders Wittrup Delivery is currently the biggest hurdle oligonucleotide therapeutics face to become effective treatments. Oligonucleotide therapeutics not only need to…