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Oligonucleotide Therapeutics Society
Oligonucleotide Therapeutics Society
Oligonucleotide Therapeutics Society
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        • Abstracts
        • Sponsors & Exhibitors
      • 2018 Annual Meeting
        • 2018 Meeting Overview
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Taking oligonucleotide research to its full therapeutic potential

Author Archives: OTS

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  2. Article author OTS

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease

Paper of the MonthBy OTSAugust 21, 2019Leave a comment

Zeitler B, Froelich S, Marlen K, Shivak DA, Yu Q, Li D, Pearl JR, Miller JC, Zhang L, Paschon DE, Hinkley SJ, Ankoudinova I, Lam S, Guschin D, Kopan L, Cherone JM, Nguyen HB, Qiao G, Ataei Y, Mendel MC, Amora R, Surosky R, Laganiere J, Vu BJ, Narayanan A, Sedaghat Y, Tillack K, Thiede…

Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes

Antisense/RNase HBy OTSJuly 31, 2019Leave a comment

Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes …………… Kanter JE, Shao B, Kramer F, Barnhart S, Shimizu-Albergine M, Vaisar T, Graham MJ, Crooke RM, Manuel CR, Haeusler RA, Mar D, Bomsztyk K, Hokanson JE, Kinney GL, Snell-Bergeon JK, Heinecke JW, Bornfeldt KE. J Clin Invest. 2019 Jul 11;130. PubMed 00

The nuclear concentration required for antisense oligonucleotide activity in myotonic dystrophy cells

Antisense/RNase HBy OTSJuly 31, 2019Leave a comment

The nuclear concentration required for antisense oligonucleotide activity in myotonic dystrophy cells …………… van der Bent ML, Paulino da Silva Filho O, Willemse M, Hällbrink M, Wansink DG, Brock R. FASEB J. 2019 Jul 16 PubMed 00

Steric Inhibition of 5′ UTR Regulatory Elements Results in Upregulation of Human CFTR

Antisense/RNase HBy OTSJuly 31, 2019Leave a comment

Steric Inhibition of 5′ UTR Regulatory Elements Results in Upregulation of Human CFTR …………… Sasaki S, Sun R, Bui HH, Crosby JR, Monia BP, Guo S. Mol Ther. 2019 Jul 12. pii: S1525-0016(19)30312-0. PubMed 00

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