A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system

A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system …………… Alterman JF, Godinho BMDC, Hassler MR, Ferguson CM, Echeverria D, Sapp E, Haraszti RA, Coles AH, Conroy F, Miller R, Roux L, Yan P, Knox EG, Turanov AA, King RM, Gernoux G, Mueller C, Gray-Edwards HL,…

Therapeutic inhibition of microRNA-34a ameliorates aortic valve calcification via modulation of Notch1-Runx2 signaling

Therapeutic inhibition of microRNA-34a ameliorates aortic valve calcification via modulation of Notch1-Runx2 signaling …………… Toshima T, Watanabe T, Narumi T, Otaki Y, Shishido T, Aono T, Goto J, Watanabe K, Sugai T, Takahashi T, Yokoyama M, Kinoshita D, Tamura H, Kato S, Nishiyama S, Arimoto T, Takahashi H, Miyamoto T, Sadahiro M, Watanabe M. Cardiovasc…