The Novel Chemical Mechanism of the Twister Ribozyme
Wilson TJ, Liu Y, Domnick C, Kath-Schorr S, Lilley DM.
J Am Chem Soc. 2016 May 18;138(19):6151-62.
Thiolated uridine substrates and templates improve the rate and fidelity of ribozyme-catalyzed RNA copying
Prywes N, Michaels YS, Pal A, Oh SS, Szostak JW.
Chem Commun (Camb). 2016 May 5;52(39):6529-32.
Elucidation of the Biotransformation Pathways of a GalNAc3-conjugated Antisense Oligonucleotide in Rats and Monkeys
Shemesh CS, Yu RZ, Gaus HJ, Greenlee S, Post N, Schmidt K, Migawa MT, Seth PP, Zanardi TA, Prakash TP, Swayze EE, Henry SP, Wang Y.
Mol Ther Nucleic Acids. 2016 May 10;5:e319
Disposition and Pharmacology of a GalNAc3-conjugated ASO Targeting Human Lipoprotein (a) in Mice
Yu RZ, Graham MJ, Post N, Riney S, Zanardi T, Hall S, Burkey J, Shemesh CS, Prakash TP, Seth PP, Swayze EE, Geary RS, Wang Y, Henry S.
Mol Ther Nucleic Acids. 2016 May 3;5:e317.