Poly(ester amine) Composed of Polyethylenimine and Pluronic Enhance Delivery of Antisense Oligonucleotides In Vitro and in Dystrophic mdx Mice …………… Wang M, Wu B, Tucker JD, Bollinger LE, Lu P, Lu Q. Mol Ther Nucleic Acids. 2016 Aug 2;5(8):e341. PubMed 00
Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain …………… Nikan M, Osborn MF, Coles AH, Godinho BM, Hall LM, Haraszti RA, Hassler MR, Echeverria D, Aronin N, Khvorova A. Mol Ther Nucleic Acids. 2016 Aug 9;5(8):e344. PubMed 00
Establishment of a Predictive In Vitro Assay for Assessment of the Hepatotoxic Potential of Oligonucleotide Drugs …………… Sewing S, Boess F, Moisan A, Bertinetti-Lapatki C, Minz T, Hedtjaern M, Tessier Y, Schuler F, Singer T, Roth AB. PLoS One. 2016 Jul 21;11(7):e0159431. PubMed 00
Effects of Repeated Complement Activation Associated with Chronic Treatment of Cynomolgus Monkeys with 2′-O-Methoxyethyl Modified Antisense Oligonucleotide …………… Shen L, Engelhardt JA, Hung G, Yee J, Kikkawa R, Matson J, Tayefeh B, Machemer T, Giclas PC, Henry SP. Nucleic Acid Ther. 2016 Aug;26(4):236-49. PubMed 00