Independent control of the thermodynamic and kinetic properties of aptamer switches. …………… Wilson BD, Hariri AA, Thompson IAP, Eisenstein M, Soh HT. Nat Commun. 2019 Nov 7;10(1):5079. PubMed 00
Mild Innate Immune Activation Overrides Efficient Nanoparticle-Mediated RNA Delivery. …………… Lokugamage MP, Gan Z, Zurla C, Levin J, Islam FZ, Kalathoor S, Sato M, Sago CD, Santangelo PJ, Dahlman JE. Adv Mater. 2019 Nov 19:e1904905. PubMed 00
R-Loops Promote Antisense Transcription across the Mammalian Genome. …………… Tan-Wong SM, Dhir S, Proudfoot NJ. Mol Cell. 2019 Nov 21;76(4):600-616.e6. PubMed 00
Analysis of autonomic outcomes in APOLLO, a phase III trial of the RNAi therapeutic patisiran in patients with hereditary transthyretin-mediated amyloidosis. …………… González-Duarte A, Berk JL, Quan D, Mauermann ML, Schmidt HH, Polydefkis M, Waddington-Cruz M, Ueda M, Conceição IM, Kristen AV, Coelho T, Cauquil CA, Tard C, Merkel M, Aldinc E, Chen J, Sweetser…