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Oligonucleotide Therapeutics Society
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      • Rare Disease Briefing Document
    • Past Annual Meetings
      • 2019 Annual Meeting
        • Agenda
        • Abstracts
        • Sponsors & Exhibitors
      • 2018 Annual Meeting
        • 2018 Meeting Overview
        • 2018 Meeting Report
        • 2018 Award Winners
        • 2018 Photo Gallery
        • 2018 Video Gallery
      • 2017 Annual Meeting
        • 2017 Meeting Overview
        • 2017 Award Winners
        • Abstracts
        • 2017 Meeting Videos
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Taking oligonucleotide research to its full therapeutic potential

Author Archives: OTS

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  2. Article author OTS

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing

Gene editingBy OTSNovember 30, 2017Leave a comment

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing …………… Yin H, Song CQ, Suresh S, Wu Q, Walsh S, Rhym LH, Mintzer E, Bolukbasi MF, Zhu LJ, Kauffman K, Mou H, Oberholzer A, Ding J, Kwan SY, Bogorad RL, Zatsepin T, Koteliansky V, Wolfe SA, Xue W, Langer R, Anderson…

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

Gene editingBy OTSNovember 30, 2017Leave a comment

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage …………… Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR. Nature. 2017 Nov 23;551(7681):464-471. PubMed 00

Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy

Gene editingBy OTSNovember 30, 2017Leave a comment

Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy …………… Amoasii L, Long C, Li H, Mireault AA, Shelton JM, Sanchez-Ortiz E, McAnally JR, Bhattacharyya S, Schmidt F, Grimm D, Hauschka SD, Bassel-Duby R, Olson EN. Sci Transl Med. 2017 Nov 29;9(418). PubMed 00

Assembly of CRISPR ribonucleoproteins with biotinylated oligonucleotides via an RNA aptamer for precise gene editing

Gene editingBy OTSNovember 30, 2017Leave a comment

Assembly of CRISPR ribonucleoproteins with biotinylated oligonucleotides via an RNA aptamer for precise gene editing …………… Carlson-Stevermer J, Abdeen AA, Kohlenberg L, Goedland M, Molugu K, Lou M, Saha K. Nat Commun. 2017 Nov 23;8(1):1711. PubMed 00

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