RNase H sequence preferences influence antisense oligonucleotide efficiency
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The intratracheal administration of locked nucleic acid containing antisense oligonucleotides induced gene silencing and an immune-stimulatory effect in the murine lung
The intratracheal administration of locked nucleic acid containing antisense oligonucleotides induced gene silencing and an immune-stimulatory effect in the murine lung …………… Uemura Y, Hagiwara K, Kobayashi K. PLoS One. 2017 Nov 6;12(11):e0187286. PubMed 00
Translation can affect the antisense activity of RNase H1-dependent oligonucleotides targeting mRNAs
Translation can affect the antisense activity of RNase H1-dependent oligonucleotides targeting mRNAs …………… Liang XH, Nichols JG, Sun H, Crooke ST. Nucleic Acids Res. 2017 Nov 20. PubMed 00
SRSF6-regulated alternative splicing that promotes tumour progression offers a therapy target for colorectal cancer
SRSF6-regulated alternative splicing that promotes tumour progression offers a therapy target for colorectal cancer …………… Wan L, Yu W, Shen E, Sun W, Liu Y, Kong J, Wu Y, Han F, Zhang L, Yu T, Zhou Y, Xie S, Xu E, Zhang H, Lai M. Gut. 2017 Nov 7. pii: gutjnl-2017-314983. PubMed 00