Life under the Microscope: Single-Molecule Fluorescence Highlights the RNA World …………… Ray S, Widom JR, Walter NG. Chem Rev. 2018 Jan 24. PubMed 00
Antisense-mediated splicing modulation utilizes antisense oligonucleotides (ASOs) to manipulate the splicing by sterically blocking the binding of splicing factors to pre-mRNA transcripts.
I first became exposed to oligonucleotide delivery while at Merck upon the acquisition of Sirna in 2006. Part of my work at the time involved glyco
Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis
Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis …………… Huynh TV, Liao F, Francis CM, Robinson GO, Serrano JR, Jiang H, Roh J, Finn MB, Sullivan PM, Esparza TJ, Stewart FR, Mahan TE, Ulrich JD, Cole T, Holtzman DM. Neuron. 2017 Dec 6;96(5):1013-1023.e4. PubMed 00