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        • LAA Nominations
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      • Paper of the Year
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    • OTS Rare Disease Workshop
      • Rare Disease Briefing Document
    • Past Annual Meetings
      • 2019 Annual Meeting
        • Agenda
        • Abstracts
        • Sponsors & Exhibitors
      • 2018 Annual Meeting
        • 2018 Meeting Overview
        • 2018 Meeting Report
        • 2018 Award Winners
        • 2018 Photo Gallery
        • 2018 Video Gallery
      • 2017 Annual Meeting
        • 2017 Meeting Overview
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Taking oligonucleotide research to its full therapeutic potential

Author Archives: OTS

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  2. Article author OTS

Anti-miR-17 therapy delays tumorigenesis in MYC-driven hepatocellular carcinoma (HCC)

Anti-miR/antagomir, MicroRNABy OTSFebruary 28, 2018Leave a comment

Anti-miR-17 therapy delays tumorigenesis in MYC-driven hepatocellular carcinoma (HCC) …………… Dhanasekaran R, Gabay-Ryan M, Baylot V, Lai I, Mosley A, Huang X, Zabludoff S, Li J, Kaimal V, Karmali P, Felsher DW. Oncotarget. 2017 Nov 9;9(5):5517-5528. PubMed 00

DNA mismatch repair and oligonucleotide end-protection promote base-pair substitution distal from a CRISPR/Cas9-induced DNA break

Gene editingBy OTSFebruary 28, 2018Leave a comment

DNA mismatch repair and oligonucleotide end-protection promote base-pair substitution distal from a CRISPR/Cas9-induced DNA break …………… Harmsen T, Klaasen S, van de Vrugt H, Te Riele H. Nucleic Acids Res. 2018 Feb 13. PubMed 00

A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing

Gene editingBy OTSFebruary 28, 2018Leave a comment

A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing …………… Finn JD, Smith AR, Patel MC, Shaw L, Youniss MR, van Heteren J, Dirstine T, Ciullo C, Lescarbeau R, Seitzer J, Shah RR, Shah A, Ling D, Growe J, Pink M, Rohde E, Wood KM, Salomon WE, Harrington WF,…

CRISPR RNAs trigger innate immune responses in human cells

Gene editingBy OTSFebruary 28, 2018Leave a comment

CRISPR RNAs trigger innate immune responses in human cells …………… Kim S, Koo T, Jee HG, Cho HY, Lee G, Lim DG, Shin HS, Kim JS. Genome Res. 2018 Feb 22. PubMed 00

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