Eteplirsen treatment for Duchenne muscular dystrophy: Exon skipping and dystrophin production …………… Charleston JS, Schnell FJ, Dworzak J, Donoghue C, Lewis S, Chen L, Young GD, Milici AJ, Voss J, DeAlwis U, Wentworth B, Rodino-Klapac LR, Sahenk Z, Frank D, Mendell JR. Neurology. 2018 May 11. pii: 10.1212/WNL.0000000000005680. PubMed 00
Exploring PAZ/3′-overhang interaction to improve siRNA specificity. A combined experimental and modeling study …………… Alagia A, Jorge AF, Aviñó A, Cova TFGG, Crehuet R, Grijalvo S, Pais AACC, Eritja R. Chem Sci. 2018 Jan 15;9(8):2074-2086. PubMed 00
Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate …………… Liu Z, Wang J, Cheng H, Ke X, Sun L, Zhang QC, Wang HW. Cell. 2018 May 31;173(6):1549-1550. PubMed 00
An interplay of miRNA abundance and target site architecture determines miRNA activity and specificity …………… Brancati G, Großhans H. Nucleic Acids Res. 2018 Apr 20;46(7):3259–3269 PubMed 00