Lipid Nanoparticle Formulations for Enhanced Co-delivery of siRNA and mRNA
Lipid Nanoparticle Formulations for Enhanced Co-delivery of siRNA and mRNA …………… Ball RL, Hajj KA, Vizelman J, Bajaj P, Whitehead KA. Nano Lett. 2018 May 8. PubMed 00
Intratumoral CpG-B promotes anti-tumoral neutrophil, cDC, and T cell cooperation without reprograming tolerogenic pDC
Intratumoral CpG-B promotes anti-tumoral neutrophil, cDC, and T cell cooperation without reprograming tolerogenic pDC …………… Humbert M, Guery L, Brighouse D, Lemeille S, Hugues S. Cancer Res. 2018 Mar 27. pii: canres.2549.2017. PubMed 00
Investigation into the mechanism(s) that leads to platelet decreases in cynomolgus monkeys during administration of ISIS-104838, a 2′-MOE-modified antisense oligonucleotide
Investigation into the mechanism(s) that leads to platelet decreases in cynomolgus monkeys during administration of ISIS-104838, a 2′-MOE-modified antisense oligonucleotide …………… Narayanan PK, Shen L, Curtis BR, Bourdon M, Nolan JP, Zhou F, Christian B, Gupta S, Schaubhut JL, Greenlee S, Hoffmaster C, Burel S, Witztum JL, Engelhardt JA, Henry SP. Toxicol Sci. 2018 May…
Effect of an siRNA Therapeutic Targeting PCSK9 on Atherogenic Lipoproteins: Pre-Specified Secondary End Points in ORION 1
Effect of an siRNA Therapeutic Targeting PCSK9 on Atherogenic Lipoproteins: Pre-Specified Secondary End Points in ORION 1 …………… Ray KK, Stoekenbroek RM, Kallend D, Leiter LA, Landmesser U, Wright RS, Wijngaard P, Kastelein JJ. Circulation. 2018 May 7. pii: CIRCULATIONAHA.118.034710. PubMed 00