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      • Rare Disease Briefing Document
    • Past Annual Meetings
      • 2019 Annual Meeting
        • Agenda
        • Abstracts
        • Sponsors & Exhibitors
      • 2018 Annual Meeting
        • 2018 Meeting Overview
        • 2018 Meeting Report
        • 2018 Award Winners
        • 2018 Photo Gallery
        • 2018 Video Gallery
      • 2017 Annual Meeting
        • 2017 Meeting Overview
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        • Abstracts
        • 2017 Meeting Videos
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Taking oligonucleotide research to its full therapeutic potential

Author Archives: OTS

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CRISPR-engineered T cells in patients with refractory cancer

Clinical Development, Gene editingBy OTSFebruary 29, 2020Leave a comment

CRISPR-engineered T cells in patients with refractory cancer …………… Stadtmauer EA, Fraietta JA, Davis MM, Cohen AD, Weber KL, Lancaster E, Mangan PA, Kulikovskaya I, Gupta M, Chen F, Tian L, Gonzalez VE, Xu J, Jung IY, Melenhorst JJ, Plesa G, Shea J, Matlawski T, Cervini A, Gaymon AL, Desjardins S, Lamontagne A, Salas-Mckee J,…

Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors

Gene editingBy OTSFebruary 29, 2020Leave a comment

Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors …………… Doman JL, Raguram A, Newby GA, Liu DR. Nat Biotechnol. 2020 Feb 10. PubMed 00

Confluence of theory and experiment reveals the catalytic mechanism of the Varkud satellite ribozyme

RibozymeBy OTSFebruary 29, 2020Leave a comment

Confluence of theory and experiment reveals the catalytic mechanism of the Varkud satellite ribozyme …………… Ganguly A, Weissman BP, Giese TJ, Li NS, Hoshika S, Rao S, Benner SA, Piccirilli JA, York DM. Nat Chem. 2020 Feb;12(2):193-201. PubMed 00

High-throughput identification of synthetic riboswitches by barcode-free amplicon-sequencing in human cells

RibozymeBy OTSFebruary 29, 2020Leave a comment

High-throughput identification of synthetic riboswitches by barcode-free amplicon-sequencing in human cells …………… Strobel B, Spöring M, Klein H, Blazevic D, Rust W, Sayols S, Hartig JS, Kreuz S. Nat Commun. 2020 Feb 5;11(1):714. PubMed 00

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